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资源有限环境下 HIV 诊断后延迟进入 HIV 医疗护理的相关因素:来自印度队列研究的数据。

Factors associated with delayed entry into HIV medical care after HIV diagnosis in a resource-limited setting: Data from a cohort study in India.

机构信息

Department of Infectious Diseases, Rural Development Trust Hospital , Bathalapalli, AP , India.

出版信息

PeerJ. 2013 Jun 18;1:e90. doi: 10.7717/peerj.90. Print 2013.

Abstract

Studies from sub-Saharan Africa have shown that a substantial proportion of patients diagnosed with HIV enter into HIV medical care late. However, data from low or middle-income countries outside Africa are scarce. In this study, we investigated risk factors associated with delayed entry into care stratified by gender in a large cohort study in India. 7701 patients were diagnosed with HIV and 5410 entered into care within three months of HIV diagnosis. Nearly 80% entered into care within a year, but most patients who did not enter into care within a year remained lost to follow up or died. Patient with risk factors related to having a low socio-economic status (poverty, being homeless, belonging to a disadvantaged community and illiteracy) were more likely to enter into care late. In addition, male gender and being asymptomatic at the moment of HIV infection were factors associated with delayed entry into care. Substantial gender differences were found. Younger age was found to be associated with delayed entry in men, but not in women. Widows and unmarried men were more likely to enter into care within three months. Women belonging to disadvantaged communities or living far from a town were more likely to enter into care late. The results of this study highlight the need to improve the linkage between HIV diagnosis and HIV treatment in India. HIV programmes should monitor patients diagnosed with HIV until they engage in HIV medical care, especially those at increased risk of attrition.

摘要

撒哈拉以南非洲的研究表明,相当一部分被诊断患有 HIV 的患者进入 HIV 医疗保健系统较晚。然而,来自非洲以外的低收入和中等收入国家的数据却很少。在这项研究中,我们调查了在印度的一项大型队列研究中按性别分层的与延迟进入护理相关的风险因素。7701 名患者被诊断患有 HIV,其中 5410 名在 HIV 诊断后三个月内进入护理。近 80%的人在一年内进入护理,但大多数一年内未进入护理的患者仍失访或死亡。具有与社会经济地位较低相关的风险因素的患者(贫困、无家可归、属于弱势群体社区和文盲)更有可能延迟进入护理。此外,男性和感染 HIV 时无症状是延迟进入护理的相关因素。研究发现存在显著的性别差异。在男性中,年龄较小与延迟进入护理有关,但在女性中并非如此。寡妇和未婚男性更有可能在三个月内进入护理。属于弱势群体社区或远离城镇的女性更有可能延迟进入护理。这项研究的结果强调了需要改善印度 HIV 诊断与 HIV 治疗之间的联系。HIV 规划应监测被诊断患有 HIV 的患者,直到他们接受 HIV 医疗保健,特别是那些有较高流失风险的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f490/3691786/84f58929f134/peerj-01-90-g001.jpg

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