Masoumi Seyyedeh Zahra, Poorolajal Jalal, Keramat Afsaneh, Moosavi Seyyed Abbas
Dept. of Reproductive Health, School of Nursing & Midwifery, Shahroud University of Medical Sciences, Semnan, Iran.
Iran J Public Health. 2013 May 1;42(5):458-66. Print 2013.
Several studies have been conducted in Iran in order to investigate the prevalence of depression among infertile couples. However, there is a remarkable diversity among the results. This meta-analysis was conducted to estimate an overall prevalence rate of depression among infertile couples in Iran.
International and national electronic databases were searched up to June 2011 including MEDLINE, Science Citation Index Expanded, Scopus, SID, MagIran, and IranMedex as well as conference databases. Furthermore, reference lists of articles were screened and the studies' authors were contacted for additional references. Cross-sectional studies addressing the prevalence of depression among infertile couples were included in this meta-analysis. We assessed 12 separate studies involving overall 2818 participants of which 1251 had depression.
Overall prevalence rate of depression among infertile couples was 0.47 (95% CI: 0.40, 0.55). The prevalence rate of depression was 0.44 (95% CI: 0.32, 0.56) during 2000 to 2005 and 0.50 (95% CI: 0.43, 0.57 during 2006 to 2011. The prevalence rate of depression was 0.46 (95% CI: 0.39, 0.53) among women and 0.47 (95% CI: 0.40, 0.54) among men.
Not only the prevalence of depression in infertile couples was high but also had increasing growth in recent years. Furthermore, despite many studies conducted addressing the prevalence of depression in infertile couples, there is however a remarkable diversity between the results. Thus, one can hardly give a precise estimation of the prevalence rate of depression among infertile couples in Iran now.
伊朗已经开展了多项研究以调查不孕夫妇中抑郁症的患病率。然而，研究结果存在显著差异。本荟萃分析旨在估计伊朗不孕夫妇抑郁症的总体患病率。
检索截至2011年6月的国际和国内电子数据库，包括MEDLINE、科学引文索引扩展版、Scopus、SID、MagIran和IranMedex以及会议数据库。此外，还筛选了文章的参考文献列表，并与研究作者联系以获取更多参考文献。本荟萃分析纳入了针对不孕夫妇抑郁症患病率的横断面研究。我们评估了12项独立研究，共涉及2818名参与者，其中1251人患有抑郁症。
不孕夫妇抑郁症的总体患病率为0.47（95%置信区间：0.40，0.55）。2000年至2005年期间抑郁症患病率为0.44（95%置信区间：0.32，0.56），2006年至2011年期间为0.50（95%置信区间：0.43，0.57）。女性抑郁症患病率为0.46（95%置信区间：0.39，0.53），男性为0.47（95%置信区间：0.40，0.54）。
不孕夫妇中抑郁症的患病率不仅很高，而且近年来呈上升趋势。此外，尽管针对不孕夫妇抑郁症患病率进行了许多研究，但结果之间仍存在显著差异。因此，目前很难准确估计伊朗不孕夫妇中抑郁症的患病率。
