Torre D, Issi M, Sampietro C, Fiori G P, Chelazzi G, Ferraro G
Division of Infectious Diseases, Regional Hospital and Foundation E and S Macchi, Verese, Italy.
J Clin Pathol. 1990 Jul;43(7):560-2. doi: 10.1136/jcp.43.7.560.
Plasma fibronectin (PFN) concentrations were assessed in 21 patients with AIDS, in seven with AIDS-related complex (ARC), in 17 asymptomatic seropositive patients, and in 36 age and sex matched healthy control subjects. A single radial immunodiffusion technique was used to determine PFN concentration. A significant decrease in PFN concentrations was observed in patients with ARC and AIDS (especially in those patients with Pneumocystis carinii pneumonitis). On the other hand, normal PFN concentrations were observed in asymptomatic seropositive patients. The determination of PFN concentration in patients with AIDS and ARC may contribute to the diagnosis of such patients.
对21例艾滋病患者、7例艾滋病相关综合征（ARC）患者、17例无症状血清阳性患者以及36例年龄和性别匹配的健康对照者的血浆纤维连接蛋白（PFN）浓度进行了评估。采用单向放射免疫扩散技术测定PFN浓度。在ARC患者和艾滋病患者中观察到PFN浓度显著降低（尤其是那些患有卡氏肺孢子虫肺炎的患者）。另一方面，在无症状血清阳性患者中观察到PFN浓度正常。测定艾滋病患者和ARC患者的PFN浓度可能有助于此类患者的诊断。
