Koch Institute for Integrative Cancer Research, Department of Chemical Engineering, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
Adv Mater. 2013 Sep 14;25(34):4707-13. doi: 10.1002/adma.201302025. Epub 2013 Jul 1.
Scalable methods, PRINT particle fabrication, and spray-assisted Layer-by-Layer deposition are combined to generate uniform and functional nanotechnologies with precise control over composition, size, shape, and surface functionality. A modular and tunable approach towards design of built-to-order nanoparticle systems, spray coating on PRINT particles is demonstrated to achieve technologies capable of targeted interactions with cancer cells for applications in drug delivery.
可扩展方法、PRINT 粒子制造和喷雾辅助层层沉积相结合，可生成具有精确控制组成、大小、形状和表面功能的均匀且功能化的纳米技术。通过模块化和可调谐方法设计定制的纳米粒子系统，对 PRINT 粒子进行喷雾涂层，实现了与癌细胞进行靶向相互作用的技术，可应用于药物输送。
