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牙齿内部的奥秘:牙髓干细胞。

Mystery inside the tooth: the dental pulp stem cells.

作者信息

Masthan K M K, Sankari S Leena, Babu N Aravindha, Gopalakrishnan T

机构信息

Professor & Head of the Department, Department of Oral Pathology and Microbiology, Sree Balaji Dental College & Hospital, Bharath University Pallikaranai, Chennai-600064 India.

出版信息

J Clin Diagn Res. 2013 May;7(5):945-7. doi: 10.7860/JCDR/2013/5379.2984. Epub 2013 May 1.

Abstract

Stem cells are distinguished by their ability to differentiate into different types of cells in the body and to self-replicate. During the recent years, stem cells have been used extensively in the field of medicine for the repair and regeneration of defective tissues and organs. However, the knowledge on the stem cell technology is increasing quickly in all medical disciplines and it dictates the need for new protective approaches in all fields, which include reparative dentistry. Stem cell therapy constitutes a common challenge for dentists as well as for biotechnologists. The aim of this study was to review the knowledge which was related to stem cells and to consider the possibility of use of stem cell populations and their technology in the future clinical applications, to cure diseases like Parkinsonism, Juvenile diabetes, certain forms of cancer, spinal injuries and heart problems.

摘要

干细胞的特点是能够分化成体内不同类型的细胞并进行自我复制。近年来,干细胞已在医学领域广泛用于修复和再生有缺陷的组织和器官。然而,所有医学学科中关于干细胞技术的知识都在迅速增长,这决定了包括修复牙科在内的所有领域都需要新的保护方法。干细胞治疗对牙医和生物技术专家来说都是一个共同的挑战。本研究的目的是回顾与干细胞相关的知识,并考虑在未来临床应用中使用干细胞群体及其技术来治疗帕金森病、青少年糖尿病、某些形式的癌症、脊髓损伤和心脏问题等疾病的可能性。

相似文献

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Mystery inside the tooth: the dental pulp stem cells.牙齿内部的奥秘:牙髓干细胞。
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Modern Trends in Dental Medicine: An Update for Internists.现代牙科医学趋势:内科医生的最新资讯。
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Stem cell-based approaches in dentistry.牙科领域基于干细胞的方法。
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Cancer stem cells as a predictive factor in radiotherapy.癌症干细胞作为放疗的预测因子。
Semin Radiat Oncol. 2012 Apr;22(2):151-74. doi: 10.1016/j.semradonc.2011.12.003.
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Dentin-derived BMP-2 and odontoblast differentiation.牙本质衍生的 BMP-2 和成牙本质细胞分化。
J Dent Res. 2010 Jun;89(6):603-8. doi: 10.1177/0022034510364487. Epub 2010 Mar 29.
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Cell surface biomarkers of embryonic stem cells.胚胎干细胞的细胞表面生物标志物。
Proteomics. 2008 Oct;8(19):4025-35. doi: 10.1002/pmic.200800073.

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