• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

一名儿科患者的黑棘皮病与肾上腺皮质肿瘤相关。

Acanthosis nigricans associated with an adrenocortical tumor in a pediatric patient.

作者信息

Isaacoff Elizabeth, Dimitriadi Filippina Filia, Barrows Frank, Pawel Bruce, Mattei Peter, Mostoufi-Moab Sogol

机构信息

Department of Pediatrics, The Children's Hospital of Philadelphia, 34th Street and Civic Center Boulevard, 3535 Market Street, Room 1562, Philadelphia, PA 19104, USA.

出版信息

Case Rep Endocrinol. 2013;2013:174593. doi: 10.1155/2013/174593. Epub 2013 May 30.

DOI:10.1155/2013/174593
PMID:23819073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3683467/
Abstract

Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma. Malignant AN is characterized by hyperpigmentation and velvety hyperplasia of the epidermis. This condition is generally not associated with tumors in pediatric populations or in the adrenal gland. We present a case of malignant AN in a pediatric patient with a nonmalignant, functional adrenocortical tumor.

摘要

恶性黑棘皮病（AN）是一种罕见的副肿瘤综合征，主要见于患有胃肠道腺癌的成年人。恶性AN的特征是表皮色素沉着过度和天鹅绒样增生。这种情况通常与儿科人群或肾上腺的肿瘤无关。我们报告一例患有非恶性功能性肾上腺皮质肿瘤的儿科患者发生恶性AN的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f33e/3683467/0b8132107719/CRIM.ENDOCRINOLOGY2013-174593.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f33e/3683467/0b8132107719/CRIM.ENDOCRINOLOGY2013-174593.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f33e/3683467/0b8132107719/CRIM.ENDOCRINOLOGY2013-174593.001.jpg

相似文献

1
Acanthosis nigricans associated with an adrenocortical tumor in a pediatric patient.一名儿科患者的黑棘皮病与肾上腺皮质肿瘤相关。
Case Rep Endocrinol. 2013;2013:174593. doi: 10.1155/2013/174593. Epub 2013 May 30.
2
Malignant acanthosis nigricans as a paraneoplastic manifestation of metastatic breast cancer.恶性黑棘皮病作为转移性乳腺癌的副肿瘤表现。
Int J Womens Dermatol. 2019 Mar 21;5(3):183-186. doi: 10.1016/j.ijwd.2019.03.002. eCollection 2019 Jul.
3
Acral-type Malignant Acanthosis Nigricans Associated with Gastric Adenocarcinoma.与胃腺癌相关的肢端型恶性黑棘皮病
Ann Dermatol. 2011 Oct;23(Suppl 2):S208-10. doi: 10.5021/ad.2011.23.S2.S208. Epub 2011 Oct 31.
4
Malignant acanthosis nigricans with oral manifestations in a young female: a case report and literature review.一名年轻女性的恶性黑棘皮病伴口腔表现：病例报告及文献综述
Front Oncol. 2024 Sep 24;14:1459148. doi: 10.3389/fonc.2024.1459148. eCollection 2024.
5
Oral Malignant Acanthosis Nigricans: An Early Diagnostic Sign for Ovarian Carcinoma: A Case Report.口腔恶性黑棘皮病：卵巢癌的早期诊断体征：一例报告
Clin Cosmet Investig Dermatol. 2024 Feb 7;17:359-363. doi: 10.2147/CCID.S447977. eCollection 2024.
6
Paraneoplastic type of acanthosis nigricans in patient with hepatocellular carcinoma.肝细胞癌患者的副肿瘤性黑棘皮病类型。
Adv Med Sci. 2007;52:254-6.
7
Malignant acanthosis nigricans: an early diagnostic clue.恶性黑棘皮病：一个早期诊断线索。
J Coll Physicians Surg Pak. 2010 Feb;20(2):127-9.
8
Malignant acanthosis nigricans associated with prostate cancer: a case report.与前列腺癌相关的恶性黑棘皮病：一例报告
BMC Urol. 2014 Nov 15;14:88. doi: 10.1186/1471-2490-14-88.
9
Malignant Acanthosis Nigricans: An Indicator of Internal Malignancy.恶性黑棘皮病：一种体内恶性肿瘤的指标。
J Coll Physicians Surg Pak. 2019 Sep;29(9):888-890. doi: 10.29271/jcpsp.2019.09.888.
10
Co-occurrence of acanthosis nigricans and bladder adenocarcinoma - case report.黑棘皮病与膀胱腺癌并存——病例报告
Contemp Oncol (Pozn). 2013;17(3):327-30. doi: 10.5114/wo.2013.35287. Epub 2013 Jun 28.

引用本文的文献

1
Idiopathic extensive acanthosis nigricans with a variant of the epidermal growth factor receptor.伴有表皮生长因子受体变异型的特发性泛发性黑棘皮病
JAAD Case Rep. 2020 Jan 16;6(2):79-82. doi: 10.1016/j.jdcr.2019.10.023. eCollection 2020 Feb.

本文引用的文献

1
Cutaneous paraneoplasia.皮肤副肿瘤综合征。
Clin Dermatol. 2011 Sep-Oct;29(5):541-7. doi: 10.1016/j.clindermatol.2010.09.022.
2
Malignant acanthosis nigricans in a 2 year old child with Wilm's Tumour.一名患有肾母细胞瘤的2岁儿童出现恶性黑棘皮病。
Indian J Dermatol Venereol Leprol. 1998 Jan-Feb;64(1):29-30.
3
Malignant acanthosis nigricans with enhanced expression of fibroblast growth factor receptor 3.伴有成纤维细胞生长因子受体3表达增强的恶性黑棘皮病
Acta Derm Venereol. 2009;89(4):435-7. doi: 10.2340/00015555-0666.
4
Hypochondroplasia and Acanthosis nigricans: a new syndrome due to the p.Lys650Thr mutation in the fibroblast growth factor receptor 3 gene?软骨发育不全与黑棘皮症：成纤维细胞生长因子受体3基因p.Lys650Thr突变导致的一种新综合征？
Eur J Endocrinol. 2008 Sep;159(3):243-9. doi: 10.1530/EJE-08-0393. Epub 2008 Jun 26.
5
Epidermal manifestations of internal malignancy.内脏恶性肿瘤的表皮表现。
Dermatol Clin. 2008 Jan;26(1):17-29, vii. doi: 10.1016/j.det.2007.08.008.
6
Familial acanthosis nigricans due to K650T FGFR3 mutation.由K650T FGFR3突变引起的家族性黑棘皮病。
Arch Dermatol. 2007 Sep;143(9):1153-6. doi: 10.1001/archderm.143.9.1153.
7
Biology, clinical characteristics, and management of adrenocortical tumors in children.儿童肾上腺皮质肿瘤的生物学特性、临床特征及治疗
Pediatr Blood Cancer. 2005 Sep;45(3):265-73. doi: 10.1002/pbc.20318.
8
Clinical and outcome characteristics of children with adrenocortical tumors: a report from the International Pediatric Adrenocortical Tumor Registry.肾上腺皮质肿瘤患儿的临床及预后特征：来自国际儿科肾上腺皮质肿瘤登记处的报告
J Clin Oncol. 2004 Mar 1;22(5):838-45. doi: 10.1200/JCO.2004.08.085.
9
Adrenal cortical neoplasms in the pediatric population: a clinicopathologic and immunophenotypic analysis of 83 patients.儿科人群中的肾上腺皮质肿瘤：83例患者的临床病理及免疫表型分析
Am J Surg Pathol. 2003 Jul;27(7):867-81. doi: 10.1097/00000478-200307000-00001.
10
Paraneoplastic dermatoses.副肿瘤性皮肤病
Dermatol Clin. 2002 Jul;20(3):523-32. doi: 10.1016/s0733-8635(02)00015-3.