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用于在各种临床和非临床环境中管理志贺氏菌的噬菌体。

Bacteriophages for managing Shigella in various clinical and non-clinical settings.

作者信息

Goodridge Lawrence D

机构信息

Department of Food Science and Agricultural Chemistry; Faculty of Agricultural and Environmental Sciences; McGill University; Montreal, QC Canada.

出版信息

Bacteriophage. 2013 Jan 1;3(1):e25098. doi: 10.4161/bact.25098. Epub 2013 May 21.

DOI:10.4161/bact.25098
PMID:23819110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3694061/
Abstract

The control of shigellosis in humans enjoys a prominent position in the history of bacteriophage therapy. d'Herelle first demonstrated the efficacy of phage therapy by curing 4 patients of shigellosis, and several subsequent studies confirmed the ability of phages to reduce based infection. spp continue to cause millions of illnesses and deaths each year and the use of phages to control the disease in humans and the spread of the bacteria within food and water could point the way forward to the effective management of an infectious disease with global influence.

摘要

在噬菌体治疗的历史中，人类志贺氏菌病的控制占据着显著地位。德赫雷尔首次通过治愈4例志贺氏菌病患者证明了噬菌体治疗的有效性，随后的多项研究证实了噬菌体减少感染的能力。志贺氏菌每年仍导致数百万人患病和死亡，利用噬菌体控制人类疾病以及食品和水中细菌的传播，可能为有效管理这种具有全球影响力的传染病指明方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/a2e45704e4b8/bact-3-e25098-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/b8141b8b46fc/bact-3-e25098-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/6ba674d6df05/bact-3-e25098-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/a2e45704e4b8/bact-3-e25098-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/b8141b8b46fc/bact-3-e25098-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/6ba674d6df05/bact-3-e25098-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9987/3694061/a2e45704e4b8/bact-3-e25098-g3.jpg

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