Boyle Patricia A, Yu Lei, Gamble Keith J, Bennett David A
Rush University Medical Center, Rush Alzheimer's Disease Center, Chicago, Illinois, United States of America ; Department of Behavioral Sciences, Rush University Medical Center, Chicago, Illinois, United States of America.
PLoS One. 2013 Jun 27;8(6):e67376. doi: 10.1371/journal.pone.0067376. Print 2013.
Temporal discounting is an important determinant of many health and financial outcomes, but we are not aware of studies that have examined the association of temporal discounting with mortality.
Participants were 406 older persons without dementia from the Rush Memory and Aging Project, a longitudinal cohort study of aging. Temporal discounting was measured using standard preference elicitation questions. Individual discount rates were estimated using a well-established hyperbolic function and used to predict the risk of mortality during up to 5 years of follow-up.
The mean estimate of discounting was 0.45 (SD = 0.33, range: 0.08-0.90), with higher scores indicating a greater propensity to prefer smaller immediate rewards over larger but delayed ones. During up to 5 years of follow-up (mean = 3.6 years), 62 (15% of 406) persons died. In a proportional hazards model adjusted for age, sex, and education, temporal discounting was associated with an increased risk of mortality (HR = 1.103, 95% CI 1.024, 1.190, p = 0.010). Thus, a person with the highest discount rate (score = 0.90) was about twice more likely to die over the study period compared to a person with the lowest discount rate (score = 0.08). Further, the association of discounting with mortality persisted after adjustment for the level of global cognitive function, the burden of vascular risk factors and diseases, and an indicator of psychological well being (i.e., purpose in life).
Temporal discounting is associated with an increased risk of mortality in old age after accounting for global cognitive function and indicators of physical and mental health.
时间折扣是许多健康和财务结果的重要决定因素,但我们尚未发现有研究探讨时间折扣与死亡率之间的关联。
参与者为拉什记忆与衰老项目中的406名无痴呆的老年人,该项目是一项关于衰老的纵向队列研究。使用标准的偏好诱导问题来测量时间折扣。个体折扣率通过一个成熟的双曲线函数进行估计,并用于预测长达5年随访期间的死亡风险。
折扣的平均估计值为0.45(标准差=0.33,范围:0.08 - 0.90),分数越高表明比起更大但延迟的奖励,更倾向于选择更小的即时奖励的倾向越大。在长达5年的随访期间(平均=3.6年),62人(406人的15%)死亡。在调整了年龄、性别和教育程度的比例风险模型中,时间折扣与死亡风险增加相关(风险比=1.103,95%置信区间1.024,1.190,p=0.010)。因此,在研究期间,折扣率最高(分数=0.90)的人死亡的可能性大约是折扣率最低(分数=0.0)的人的两倍。此外,在调整了全球认知功能水平、血管危险因素和疾病负担以及心理健康指标(即生活目的)后,折扣与死亡率之间的关联仍然存在。
在考虑了全球认知功能以及身心健康指标后,时间折扣与老年人群死亡风险增加相关。