Tretli S, Magnus K
Cancer Registry of Norway, Institute of Epidemiological Cancer Research, Montebello, Oslo.
Int J Cancer. 1990 Aug 15;46(2):165-72. doi: 10.1002/ijc.2910460204.
The height and weight of 570,000 Norwegian women, aged 30-69 years, were measured and the subjects were then followed up for 6-18 years with regard to uterine corpus cancer morbidity and mortality. The analysis reveals that both height and Quetelet's index are risk factors for uterine corpus cancer. The risk for women belonging to the 5th quintile of both height and Quetelet's index is 3.2 times higher than the risk for women in the 1st quintile of both factors. It is argued that both height and Quetelet's index express a common etiological mechanism and that this mechanism is probably connected to the early phase of the disease. Body size expressed through body surface area reveals about the same strength of association as Quetelet's index. It is calculated that if women in the 5th quintile of Quetelet's index belonged to the 4th quintile instead, there would be about 10% fewer cases of uterine corpus cancer.
对570,000名年龄在30至69岁之间的挪威女性进行了身高和体重测量，随后对这些受试者进行了6至18年的随访，以了解子宫体癌的发病率和死亡率。分析显示，身高和奎特利指数均为子宫体癌的危险因素。身高和奎特利指数均处于第5五分位数的女性的患病风险比这两个因素均处于第1五分位数的女性高3.2倍。有人认为，身高和奎特利指数都表达了一种共同的病因机制，并且这种机制可能与疾病的早期阶段有关。通过体表面积表示的体型显示出与奎特利指数大致相同的关联强度。据计算，如果奎特利指数处于第5五分位数的女性改为处于第4五分位数，子宫体癌病例将减少约10%。
