戊二醛对肠道病毒的灭活作用。
Inactivation of enterovirus by glutaraldehyde.
作者信息
Saitanu K, Lund E
出版信息
Appl Microbiol. 1975 May;29(5):571-4. doi: 10.1128/am.29.5.571-574.1975.
Abstract
A study on the rate of inactivation by glutaraldehyde of coxsackievirus was conducted using different concentrations, temperatures, and pH values. It was found, that 2 percent glutaraldehyde at pH 7.4 and 25 C, as recommended for a sporicide, reduced the titer of infectious virus by 2 log10U in 1 min or less. The reduction was not negatively affected by high concentrations of organic matter (serum and animal spillings) in the reaction mixtures.
摘要
使用不同浓度、温度和pH值对戊二醛使柯萨奇病毒失活的速率进行了一项研究。结果发现，作为杀孢子剂推荐的pH值7.4、25℃条件下的2%戊二醛，在1分钟或更短时间内可使感染性病毒滴度降低2 log10U。反应混合物中高浓度的有机物（血清和动物排泄物）对这种降低没有负面影响。
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