Jarcho Johanna M, Leibenluft Ellen, Walker Olga Lydia, Fox Nathan A, Pine Daniel S, Nelson Eric E
Section on Developmental and Affective Neuroscience, National Institute of Mental Health, National Institutes of Health, 9000 Rockville Pike, Building 15 K, Bethesda, MD 20892, USA.
Section on Bipolar Spectrum Disorders, National Institute of Mental Health, Bethesda, MD 20892, USA.
Biol Mood Anxiety Disord. 2013 Jul 12;3:14. doi: 10.1186/2045-5380-3-14. eCollection 2013.
Social Anxiety Disorder (SAD) is a common and debilitating condition that typically manifests in adolescence. Here we describe cognitive factors engaged by brain-imaging tasks, which model the peer-based social interactions that evoke symptoms of SAD. We then present preliminary results from the Virtual School paradigm, a novel peer-based social interaction task. This paradigm is designed to investigate the neural mechanisms mediating individual differences in social response flexibility and in participants' responses to uncertainty in social contexts. We discuss the utility of this new paradigm for research on brain function and developmental psychopathology.
社交焦虑障碍（SAD）是一种常见且使人衰弱的病症，通常在青春期出现。在此，我们描述了脑成像任务所涉及的认知因素，这些任务模拟了引发社交焦虑障碍症状的基于同伴的社交互动。然后，我们展示了虚拟学校范式的初步结果，这是一种新颖的基于同伴的社交互动任务。该范式旨在研究介导社交反应灵活性个体差异以及参与者对社交情境中不确定性反应的神经机制。我们讨论了这种新范式在脑功能和发展性精神病理学研究中的效用。
