Sawan Mohamad, Salam Muhammad T, Le Lan Jérôme, Kassab Amal, Gelinas Sébastien, Vannasing Phetsamone, Lesage Frédéric, Lassonde Maryse, Nguyen Dang K
Polystim Neurotechnologies Laboratory, Electrical Engineering Department, Polytechnique Montréal, QC H3T1J4, Canada.
IEEE Trans Biomed Circuits Syst. 2013 Apr;7(2):186-95. doi: 10.1109/TBCAS.2013.2255595.
In this paper, we present the design and implementation of a wireless wearable electronic system dedicated to remote data recording for brain monitoring. The reported wireless recording system is used for a) simultaneous near-infrared spectrometry (NIRS) and scalp electro-encephalography (EEG) for noninvasive monitoring and b) intracerebral EEG (icEEG) for invasive monitoring. Bluetooth and dual radio links were introduced for these recordings. The Bluetooth-based device was embedded in a noninvasive multichannel EEG-NIRS system for easy portability and long-term monitoring. On the other hand, the 32-channel implantable recording device offers 24-bit resolution, tunable features, and a sampling frequency up to 2 kHz per channel. The analog front-end preamplifier presents low input-referred noise of 5 μ VRMS and a signal-to-noise ratio of 112 dB. The communication link is implemented using a dual-band radio frequency transceiver offering a half-duplex 800 kb/s data rate, 16.5 mW power consumption and less than 10(-10) post-correction Bit-Error Rate (BER). The designed system can be accessed and controlled by a computer with a user-friendly graphical interface. The proposed wireless implantable recording device was tested in vitro using real icEEG signals from two patients with refractory epilepsy. The wirelessly recorded signals were compared to the original signals recorded using wired-connection, and measured normalized root-mean square deviation was under 2%.
在本文中，我们介绍了一种用于脑监测远程数据记录的无线可穿戴电子系统的设计与实现。所报道的无线记录系统用于：a）同步近红外光谱法（NIRS）和头皮脑电图（EEG）进行无创监测；b）颅内脑电图（icEEG）进行有创监测。这些记录引入了蓝牙和双无线电链路。基于蓝牙的设备嵌入到无创多通道EEG-NIRS系统中，便于携带和长期监测。另一方面，32通道可植入记录设备具有24位分辨率、可调节功能，每通道采样频率高达2 kHz。模拟前端前置放大器的输入参考噪声低至5 μ VRMS，信噪比为112 dB。通信链路采用双频段射频收发器实现，提供半双工800 kb/s的数据速率、16.5 mW的功耗以及小于10^(-10)的校正后误码率（BER）。所设计的系统可通过具有用户友好图形界面的计算机进行访问和控制。所提出的无线可植入记录设备在体外使用来自两名难治性癫痫患者的真实icEEG信号进行了测试。将无线记录的信号与使用有线连接记录的原始信号进行比较，测得的归一化均方根偏差低于2%。
