IEEE Trans Biomed Circuits Syst. 2010 Aug;4(4):232-8. doi: 10.1109/TBCAS.2010.2048430.
In this paper, we present a bacteria growth monitoring technique using a complementary metal-oxide semiconductor capacitive sensor. The proposed platform features a differential capacitive readout architecture with two interdigitized reference and sensing electrodes. These electrodes are exposed to pure Luria-Bertani (LB) medium and Escherichia Coli (E. Coli) bacteria suspended in the LB medium, respectively. In order to direct the solutions toward the electrodes, two microfluidic channels are implemented atop the electrodes through a direct-write assembly technique. We thereafter demonstrate and discuss the experimental results by using two different bacteria concentrations in the order of 10(6) and 10(7) per 1 mL in the LB medium.
本文提出了一种使用互补金属氧化物半导体电容传感器监测细菌生长的技术。所提出的平台采用具有两个叉指式参考和传感电极的差分电容读出架构。这些电极分别暴露于纯 LB 培养基和悬浮在 LB 培养基中的大肠杆菌 (E. Coli) 细菌。为了将溶液引导到电极上，通过直写组装技术在电极上方实现了两个微流道。此后，我们使用 LB 培养基中 10(6)和 10(7) 每 1 毫升的两种不同细菌浓度来演示和讨论实验结果。
