Kobrick J L, Johnson R F, McMenemy D J
U.S. Army Research Institute of Environmental Medicine, Natick, MA 01760-5007.
Aviat Space Environ Med. 1990 Jul;61(7):622-30.
Visual acuity, phoria, stereopsis, and contrast sensitivity were assessed over 6 h of continued exposure to combinations of atropine (2 mg) and 2-PAM chloride (600 mg), severe heat/humidity (95 degrees F (35 degrees C); 60% RH), and wearing either the U.S. Army battle dress uniform (BDU) or the BDU and the impermeable chemical protective clothing (MOPP-IV). Subjects were able to complete all 6 h of testing under severe heat when wearing BDU's, but only lasted 2 h under the same severe heat when wearing MOPP-IV. Acuity and phoria were significantly impaired by the drug in the BDU conditions. Acuity, phoria and stereopsis were all significantly impaired by heat, drug and continued exposure under MOPP-IV. Acuity was significantly impaired by drug even during the first 2 h of heat exposure in MOPP-IV. Contrast sensitivity was impaired mainly by continued heat exposure in MOPP-IV.
在持续暴露于阿托品(2毫克)和氯解磷定(600毫克)的组合、高温/高湿度环境(华氏95度(35摄氏度);相对湿度60%)以及穿着美国陆军战斗服(BDU)或BDU与不透水化学防护服(MOPP-IV)的情况下,对视力、隐斜视、立体视觉和对比敏感度进行了6小时的评估。受试者穿着BDU时能够在高温环境下完成全部6小时的测试,但穿着MOPP-IV时在相同高温环境下仅持续了2小时。在BDU条件下,药物显著损害了视力和隐斜视。在MOPP-IV条件下,高温、药物和持续暴露均显著损害了视力、隐斜视和立体视觉。即使在MOPP-IV环境下高温暴露的前2小时,药物也显著损害了视力。在MOPP-IV中,对比敏感度主要受到持续高温暴露的损害。