Sheese Brad E, Rothbart Mary K, Voelker Pascale M, Posner Michael I
Department of Psychology, Illinois Wesleyan University, 201 E. Beecher Strect, Bloomington, IL 61701, USA.
Child Dev Res. 2012 Jan 1;2012:863242. doi: 10.1155/2012/863242.
The dopamine receptor D4 gene (DRD4) 7-repeat allele has been found to interact with environmental factors such as parenting in children and peer attitudes in adults to influence aspects of behavior such as risk taking. We previously found that in toddlers, lower-quality parenting in combination with the 7-repeat allele of the DRD4 gene was associated with greater parent-reported Sensation Seeking (SS), but was unrelated to Effortful Control (EC). We now report findings from a followup assessment with the same sample of children showing that parenting quality interacts with the presence of the 7-repeat allele to predict EC in 3-to 4-year-old children. The change in these patterns of results may reflect the increased role of the executive attention network in older children and adults. However, due to the small sample size ( = 52) and the novelty of the results, these findings should be treated with caution and considered preliminary until they are replicated in an independent sample.
已发现多巴胺受体D4基因（DRD4）的7重复等位基因与环境因素相互作用，如儿童时期的养育方式和成人时期的同伴态度，以影响冒险等行为方面。我们之前发现，在幼儿中，质量较低的养育方式与DRD4基因的7重复等位基因相结合，与父母报告的感觉寻求（SS）增加有关，但与努力控制（EC）无关。我们现在报告对同一组儿童进行后续评估的结果，表明养育质量与7重复等位基因的存在相互作用，可预测3至4岁儿童的EC。这些结果模式的变化可能反映了执行注意力网络在大龄儿童和成人中作用的增加。然而，由于样本量较小（n = 52）且结果新颖，这些发现应谨慎对待，并视为初步结果，直至在独立样本中得到重复验证。
