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针对新被建议开始抗逆转录病毒治疗的青少年,基于计算机的动机干预对治疗依从性的初步可行性。

The initial feasibility of a computer-based motivational intervention for adherence for youth newly recommended to start antiretroviral treatment.

作者信息

Outlaw Angulique Y, Naar-King Sylvie, Tanney Mary, Belzer Marvin E, Aagenes Anna, Parsons Jeffrey T, Merlo Lisa J

机构信息

a Department of Pediatrics , Wayne State University School of Medicine , Detroit , MI , USA.

出版信息

AIDS Care. 2014 Jan;26(1):130-5. doi: 10.1080/09540121.2013.813624. Epub 2013 Jul 22.

Abstract

Young people represent the largest number of new HIV infections, thus youth living with HIV (YLH) are likely to be the largest group to initiate antiretroviral treatment (ART). Adherence patterns for behaviorally infected YLH are not adequate to effectively manage the disease; therefore, novel interventions are needed to improve medication adherence. The purpose of the current study, which will precede a randomized controlled trial, was to assess the initial feasibility of an individually tailored computer-based two-session interactive motivational interviewing (MI) intervention for YLH newly recommended to start ART. Intervention development occurred in collaboration with three youth advisory groups. Ten youth (ages 18-24) were recruited to participate in this study. Participants completed the intervention online. Intervention components focused on medication adherence (rating perceived importance and confidence, and goal setting). Retention was 100% for both intervention sessions. All participants (n=10) felt medication adherence was important, but 80% felt confident they could manage their adherence to HIV medications. Ninety percent of participants set the goal of taking their HIV medications exactly as prescribed and reported success achieving this goal at follow-up. Additionally, participants were satisfied with the quality of the sessions and the amount of assistance they received for managing their adherence to HIV medications (90% participants for Session 1; 89% for Session 2). Per exit interview responses, participants felt that the intervention made them think more about their health and was a motivator for them to take better care of their health. In conclusion, the intervention was feasible for YLH enrolled in the study.

摘要

年轻人是新增艾滋病毒感染病例最多的群体,因此感染艾滋病毒的青年(YLH)很可能是开始接受抗逆转录病毒治疗(ART)的最大群体。行为感染的YLH的服药依从模式不足以有效控制病情;因此,需要新的干预措施来提高药物依从性。本研究在一项随机对照试验之前进行,目的是评估一种针对新推荐开始接受ART治疗的YLH的、基于计算机的、量身定制的两阶段交互式动机性访谈(MI)干预措施的初步可行性。干预措施的开发是与三个青年咨询小组合作进行的。招募了10名年龄在18至24岁之间的青年参与本研究。参与者通过在线方式完成干预。干预内容侧重于药物依从性(评估感知到的重要性和信心以及设定目标)。两个干预阶段的保留率均为100%。所有参与者(n = 10)都认为药物依从性很重要,但80%的人觉得自己有信心管理好艾滋病毒药物的服用。90%的参与者设定了严格按规定服用艾滋病毒药物的目标,并在随访时报告成功实现了这一目标。此外,参与者对各阶段的质量以及他们在管理艾滋病毒药物服用方面获得的帮助程度感到满意(第一阶段为90%的参与者;第二阶段为89%)。根据退出访谈的回答,参与者认为该干预措施让他们更多地思考自己的健康问题,是促使他们更好地照顾自己健康的一个动力。总之,该干预措施对参与本研究的YLH是可行的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f76/3872202/babab5caea3a/nihms-522481-f0001.jpg

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