Borås Children's Hospital, South Älvsborg's Hospital, Borås, Sweden.
Prostaglandins Leukot Essent Fatty Acids. 2013 Sep;89(4):241-4. doi: 10.1016/j.plefa.2013.06.005. Epub 2013 Jul 16.
Nervonic acid is important for white matter development and its incorporation increases rapidly in the last trimester, but few studies focus on this fatty acid. Other mother's milk, usually after term delivery, is often used for premature infants, whose mothers cannot breastfeed. The fatty acid (FA) concentrations were analyzed by gas chromatography in 12 samples of donor human milk (DHM) from five mothers, and compared to milk from 42 mothers delivering preterm infants. Fat, lactose and protein contents were compared. Nervonic acid showed sevenfold higher concentrations and LCPUFA 90% higher concentrations in premature milk compared to DHM. Linoleic acid was found in 43% higher concentrations in DHM than in premature milk. The fat and protein contents were lower in DHM. Our results suggest that studies are warranted to investigate if DHM given to premature infants may require supplementation of nervonic acid, and not only LCPUFA, protein and minerals.
神经酸对于大脑白质的发育非常重要，其在妊娠末期的摄入量迅速增加，但很少有研究关注这种脂肪酸。其他产妇的母乳，通常在足月分娩后，经常用于早产儿，因为早产儿的母亲无法进行母乳喂养。我们通过气相色谱法分析了 5 位母亲的 12 份捐赠人乳样本（DHM）中的脂肪酸（FA）浓度，并与 42 位早产儿母亲的母乳进行了比较。比较了脂肪、乳糖和蛋白质的含量。与 DHM 相比，早产儿母乳中的神经酸浓度高出 7 倍，长链多不饱和脂肪酸（LCPUFA）高出 90%。DHM 中的亚油酸含量比早产儿母乳高 43%。DHM 的脂肪和蛋白质含量较低。我们的研究结果表明，有必要研究是否需要给早产儿补充神经酸，而不仅仅是 LCPUFA、蛋白质和矿物质。
