1 University of Wisconsin Dietetics Program, Madison, WI, USA.
2 Department of Medicine, University of Wisconsin School of Medicine & Public Health, Suite 4124 MFCB, 1685 Highland Avenue, Madison, WI 53705-2281, USA.
Public Health Nutr. 2014 Apr;17(4):739-46. doi: 10.1017/S1368980013001973. Epub 2013 Jul 22.
Our objective was to determine whether a questionnaire can identify individuals with vitamin D insufficiency (VDI).
Women completed the Vitamin D & Sun (VIDSUN) questionnaire and we measured their serum 25-hydrocyvitamin D (25(OH)D) levels. We assessed the sensitivity and specificity of the questionnaire to identify VDI (25(OH)D level <50 nmol/l).
Clinical Research Unit, University of Wisconsin-Madison.
Postmenopausal women.
We recruited 609 postmenopausal women with a mean age of 61 (sd 6 years), of whom 113 (19%) had VDI. Women with VDI were more likely to be black (17% v. 2%, P < 0.001), heavier (BMI 33.0 (sd 7) kg/m2 v. 29.0 (sd 7) kg/m2, P < 0.001) and less likely to tan in the past year (49% v. 72%, P < 0.001), use sunscreen (57% v. 72%, P < 0.001) or report sun exposure in the last 3 months. They consumed less vitamin D from supplements (2.15 (sd 5.24) μg/d (86 (sd 210) IU/d) v. 4.55 (sd 8.48) μg/d (188 (sd 344) IU/d), P = 0.003). In logistic regression models, black race, BMI, suntan within the past year, sun exposure in the past 3 months, sunscreen use and supplemental vitamin D intake were the most useful questions to identify VDI. From these six items, a composite score of ≤ 2.25 demonstrated ≥89% sensitivity but ≤35% specificity for VDI.
The VIDSUN questionnaire provides an initial tool to identify postmenopausal women at high or low risk of VDI. Existing studies suggest that inclusion of physical activity and TAG levels might improve the performance of the VIDSUN questionnaire.
本研究旨在确定一份问卷能否用于识别维生素 D 不足（VDI）患者。
入组的绝经后女性填写维生素 D 与阳光（VIDSUN）问卷，并检测其血清 25-羟维生素 D（25（OH）D）水平。我们评估了该问卷识别 VDI（25（OH）D 水平＜50nmol/L）的灵敏度和特异度。
威斯康星大学麦迪逊分校临床研究中心。
绝经后女性。
共纳入 609 名绝经后女性，平均年龄 61（标准差 6 年）岁，113 名（19%）存在 VDI。VDI 患者更可能为黑人（17%比 2%，P＜0.001）、体重指数（BMI）更高（33.0（标准差 7）kg/m2比 29.0（标准差 7）kg/m2，P＜0.001）、过去 1 年中更少晒黑（49%比 72%，P＜0.001）、更少使用防晒霜（57%比 72%，P＜0.001）或报告过去 3 个月内有阳光暴露。她们摄入的维生素 D 补充剂更少（2.15（标准差 5.24）μg/d（86（标准差 210）IU/d）比 4.55（标准差 8.48）μg/d（188（标准差 344）IU/d），P=0.003）。在逻辑回归模型中，黑人种族、BMI、过去 1 年中晒黑、过去 3 个月内有阳光暴露、使用防晒霜和维生素 D 补充剂摄入量是识别 VDI 最有用的问题。这 6 个问题组成的综合评分≤2.25 对 VDI 的灵敏度≥89%但特异度≤35%。
VIDSUN 问卷提供了一种初步的工具，可用于识别 VDI 高危或低危的绝经后女性。现有研究表明，纳入体力活动和 TAG 水平可能会提高 VIDSUN 问卷的性能。
