Department of Ophthalmology, Zhongshan Hospital of Fudan University, Shanghai, China.
Graefes Arch Clin Exp Ophthalmol. 2013 Sep;251(9):2147-54. doi: 10.1007/s00417-013-2423-3. Epub 2013 Jul 20.
To compare thermal and mechanical clear corneal incision (CCI) injuries after conventional and torsional phacoemulsification.
A prospective, randomized clinical study.
A total of 80 eyes were evaluated for the profile of the incision at 1 day and 3 months postoperatively. The wound architecture was recorded with anterior segment optical coherence tomography (AS-OCT). The incisional thickness increased by thermal injury, Descemet's membrane detachment (DMD) caused by mechanical injury, the presence of endothelial gaping, loss of coaptation, and wound retraction of the conventional phaco group and the torsional phaco group were compared.
The corneal thickness at the incision site of the torsional ultrasound group was significantly lower than the conventional group compared to at the first postoperative visit (1187.55 ± 75.66, 1233.62 ± 85.87, P = .013). However, this thickness was similar between the two groups at 3 months postoperatively. The central endothelial cell loss was significantly lower in the torsional ultrasound group after 3 months (417 ± 143, 322 ± 130, P = .003). There was a positive correlation between cumulated dissipated energy (CDE) and the incisional corneal thickness change that was observed by AS-OCT. Other OCT outcome parameters (such as endothelial gap, DMD, epithelial gap, and uncoaptation) that may be caused by mechanical injury did not differ significantly between the groups on postoperative day one or after 3 months.
The torsional ultrasound mode may provide a lower level of phacoemulsification time and energy and induce less incisional corneal thickness caused by thermal injury in the early postoperative period. The long-term wound healing appeared the same in both ultrasound mode groups.
比较传统超声乳化和扭转超声乳化对角膜热损伤和机械性损伤的影响。
前瞻性随机对照临床研究。
共 80 只眼在术后 1 天和 3 个月时评估切口形态。采用眼前节光学相干断层扫描(AS-OCT)记录切口结构。比较常规组和扭转组角膜热损伤导致的切口厚度增加、机械损伤导致的后弹力层脱离(DMD)、内皮细胞间隙、贴合丢失和切口回缩。
与术后第 1 天相比,扭转超声组角膜切口处的角膜厚度明显低于常规组(1187.55 ± 75.66、1233.62 ± 85.87,P =.013)。然而,两组在术后 3 个月时的厚度相似。术后 3 个月,扭转超声组中央角膜内皮细胞丢失明显低于常规组(417 ± 143、322 ± 130,P =.003)。AS-OCT 观察到的累积耗散能量(CDE)与切口角膜厚度变化呈正相关。其他 OCT 结果参数(如内皮间隙、DMD、上皮间隙和贴合丢失)在术后第 1 天或术后 3 个月时在两组之间差异无统计学意义。
扭转超声模式可能在术后早期提供较低的超声乳化时间和能量,并减少热损伤引起的切口角膜厚度增加。两种超声模式组的长期伤口愈合情况相同。