Melander Christian, Moeller Peter D R, Ballard T Eric, Richards Justin J, Huigens Robert W, Cavanagh John
Department of Chemistry, North Carolina State University, Raleigh, NC 27695-8204, USA.
Int Biodeterior Biodegradation. 2009 Jun;63(4):529-532. doi: 10.1016/j.ibiod.2008.08.009.
Methods used to deter biofouling of underwater structures and marine vessels present a serious environmental issue and are both problematic and costly for government and commercial marine vessels worldwide. Current antifouling methods include compounds that are toxic to aquatic wildlife and marine ecosystems. Dihydrooroidin (DHO) was shown to completely inhibit biofilms at 100 μM in a static biofilm inhibition assay giving precedence for the inhibition of other marine-biofilm-forming organisms. Herein we present DHO as an effective paint-based, non-cytotoxic, antifouling agent against marine biofouling processes in a marine mesocosm.
用于防止水下结构和船舶生物污损的方法带来了严重的环境问题,对全球范围内的政府和商业船舶来说都存在问题且成本高昂。目前的防污方法包括对水生野生动物和海洋生态系统有毒的化合物。在静态生物膜抑制试验中,二氢类胡萝卜素(DHO)在100μM时可完全抑制生物膜,这使其在抑制其他海洋生物膜形成生物方面具有优势。在此,我们展示了DHO作为一种有效的基于涂料的、无细胞毒性的防污剂,可在海洋中尺度生态系统中对抗海洋生物污损过程。