Reilly P A, Evison G, McHugh N J, Maddison P J
Royal National Hospital for Rheumatic Diseases, Bath, England, UK.
J Rheumatol. 1990 Jun;17(6):777-84.
Hand and foot radiographs of 51 patients with systemic lupus erythematosus (SLE) were examined prospectively and correlations made between radiological, clinical and serological data. At least one abnormality was present in the hands of 53% and in the feet of 66.7% of patients. Jaccoud's type arthropathy affected the hands of 12% and the feet of 8% of patients. Erosions of the ulnar styloids were common (27.5%) but their presence did not correlate with any clinical or laboratory feature of SLE. Antibodies to U1 RNP correlated with hand deformity, while severity of radiological damage related mainly to disease duration.
对51例系统性红斑狼疮(SLE)患者的手部和足部X线片进行了前瞻性检查,并对放射学、临床和血清学数据进行了相关性分析。至少53%的患者手部和66.7%的患者足部存在至少一项异常。Jaccoud型关节病累及12%的患者手部和8%的患者足部。尺骨茎突侵蚀很常见(27.5%),但其存在与SLE的任何临床或实验室特征均无相关性。抗U1 RNP抗体与手部畸形相关,而放射学损伤的严重程度主要与疾病持续时间有关。