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经颅直流电刺激左前额叶皮层能促进工具使用中的认知灵活性。

Noninvasive transcranial direct current stimulation over the left prefrontal cortex facilitates cognitive flexibility in tool use.

出版信息

Cogn Neurosci. 2013;4(2):81-9. doi: 10.1080/17588928.2013.768221.

DOI:10.1080/17588928.2013.768221
PMID:23894253
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3719984/
Abstract

Recent neuroscience evidence suggests that some higher-order tasks might benefit from a reduction in sensory filtering associated with low levels of cognitive control. Guided by neuroimaging findings, we hypothesized that cathodal (inhibitory) transcranial direct current stimulation (tDCS) will facilitate performance in a flexible use generation task. Participants saw pictures of artifacts and generated aloud either the object’s common use or an uncommon use for it, while receiving cathodal tDCS (1.5 mA) either over left or right PFC, or sham stimulation. A forward digit span task served as a negative control for potential general effects of stimulation. Analysis of voice-onset reaction times and number of responses generated showed significant facilitative effects of left PFC stimulation for the uncommon, but not the common use generation task and no effects of stimulation on the control task. The results support the hypothesis that certain tasks may benefit from a state of diminished cognitive control.

摘要

最近的神经科学证据表明,一些高级任务可能受益于与低水平认知控制相关的感觉过滤的减少。受神经影像学发现的启发,我们假设阴极(抑制性)经颅直流电刺激(tDCS)将促进灵活使用生成任务的表现。参与者看到了人工制品的图片,并大声说出物体的常见用途或不常见用途,同时接受阴极 tDCS(1.5 mA)在左或右 PFC 上,或假刺激。正向数字跨度任务作为刺激潜在一般效应的阴性对照。对语音起始反应时间和生成的响应数量的分析表明,左 PFC 刺激对不常见但对常见用途生成任务没有影响,对控制任务也没有影响。结果支持这样一种假设,即某些任务可能受益于认知控制减弱的状态。

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