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青少年和成年人中耐大环内酯类肺炎支原体肺炎:临床特征、药敏情况和治疗效果。

Macrolide-resistant Mycoplasma pneumoniae pneumonia in adolescents and adults: clinical findings, drug susceptibility, and therapeutic efficacy.

机构信息

Department of Internal Medicine 1.

出版信息

Antimicrob Agents Chemother. 2013 Oct;57(10):5181-5. doi: 10.1128/AAC.00737-13. Epub 2013 Jul 29.

Abstract

We investigated differences in the clinical findings between 30 patients with macrolide-resistant Mycoplasma pneumoniae pneumonia and 43 patients with macrolide-sensitive M. pneumoniae pneumonia in adolescents and adults. No differences in clinical presentation were observed between the two groups. Among patients with macrolide-resistant Mycoplasma pneumoniae pneumonia, treatment was more effective in the groups that received quinolones and minocycline than in the group that received macrolides (P = 0.0361 and P = 0.0237, respectively).

摘要

我们研究了 30 例大环内酯类耐药肺炎支原体肺炎患者和 43 例青少年和成人大环内酯类敏感肺炎支原体肺炎患者的临床特征差异。两组患者的临床表现无差异。在大环内酯类耐药肺炎支原体肺炎患者中,接受喹诺酮类和米诺环素治疗的患者比接受大环内酯类治疗的患者治疗效果更好(分别为 P = 0.0361 和 P = 0.0237)。

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