• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

印度北阿坎德邦喜马拉雅地区种植的木香根的挥发性成分。

Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, India.

作者信息

Gwari Garima, Bhandari Ujjwal, Andola Harish Chandra, Lohani Hema, Chauhan Nirpendra

机构信息

Centre for Aromatic Plants, Industrial Estate, Selaqui, Dehradun, Uttarakhand, India.

出版信息

Pharmacognosy Res. 2013 Jul;5(3):179-82. doi: 10.4103/0974-8490.112424.

DOI:10.4103/0974-8490.112424
PMID:23901213
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3719259/
Abstract

BACKGROUND

Saussurea costus (Falc.) Lipschitz, syn Saussurea lappa C.B. Clarke, one of the best-known species within this genus, is commonly known as costus. Due to the remarkable biological activity of S. costus and its constituents it will have an appropriate place in various systems of medicines all over the globe.

OBJECTIVE

The main aim is to study the volatile constituents of S costus cultivated in Uttarakhand Himalayas.

MATERIAL AND METHODS

The volatile constituents were isolated from the root of S costus cultivated in Chamoli district of Uttrarakhand by hydro distillation and were analyzed by gas chromatography-mass spectroscopy (GC-MS).

RESULTS

A total 35 aroma compounds representing about 92.81% of the total composition were identified. Aldehyde like (7Z, 10Z, 13Z)-7, 10, 13-hexadecaterinal (25.5%) was found as a major compound including other ketones like dehydrocostus lactone (16.7%), alcohols like elemol (5.84%), γ-costol (1.80%), vulgarol B (3.14%), valerenol (4.20%), and terpinen-4-ol (1.60%), etc. Esters and acids were found to be completely absent in our samples.

CONCLUSION

S. costus volatile oil constituents are superior in terms of total identified constituents. Where relative area quantum is higher in Uttarakhand Himalayas samples, when compared with those originated to China and Korea.

摘要

背景

木香(Saussurea costus (Falc.) Lipschitz,异名 Saussurea lappa C.B. Clarke)是该属中最著名的物种之一,通常被称为木香。由于木香及其成分具有显著的生物活性,它在全球各种医学体系中都将占有一席之地。

目的

主要目的是研究在北阿坎德邦喜马拉雅地区种植的木香的挥发性成分。

材料与方法

通过水蒸馏法从北阿坎德邦查莫利县种植的木香根中分离出挥发性成分,并采用气相色谱 - 质谱联用(GC - MS)进行分析。

结果

共鉴定出 35 种香气化合物,占总成分约 92.81%。醛类如(7Z, 10Z, 13Z)-7, 10, 13 - 十六碳三烯醛(25.5%)是主要化合物,还包括其他酮类如脱氢木香内酯(16.7%)、醇类如榄香醇(5.84%)、γ - 木香醇(1.80%)、木香二醇 B(3.14%)、缬草烯醇(4.20%)和松油醇 - 4(1.60%)等。在我们的样品中未发现酯类和酸类。

结论

就已鉴定的总成分而言,木香挥发油成分较为优异。与源自中国和韩国的样品相比,北阿坎德邦喜马拉雅地区的样品中相对面积含量更高。

相似文献

1
Volatile constituents of Saussurea costus roots cultivated in Uttarakhand Himalayas, India.印度北阿坎德邦喜马拉雅地区种植的木香根的挥发性成分。
Pharmacognosy Res. 2013 Jul;5(3):179-82. doi: 10.4103/0974-8490.112424.
2
Aucklandia costus (Syn. Saussurea costus): Ethnopharmacology of an endangered medicinal plant of the himalayan region.土木香(土木香属):喜马拉雅地区濒危药用植物的民族药理学。
J Ethnopharmacol. 2020 Dec 5;263:113199. doi: 10.1016/j.jep.2020.113199. Epub 2020 Jul 27.
3
Saussurea costus: botanical, chemical and pharmacological review of an ayurvedic medicinal plant.木香:一种阿育吠陀药用植物的植物学、化学和药理学综述
J Ethnopharmacol. 2007 Apr 4;110(3):379-90. doi: 10.1016/j.jep.2006.12.033. Epub 2007 Jan 20.
4
Modulation of mammary tumour progression using murine model by ethanol root extract of Saussurea costus (falc.) lipsch.利用绵头雪莲乙醇根提取物对小鼠模型的乳腺肿瘤进展进行调节
J Ethnopharmacol. 2024 Jan 30;319(Pt 3):117302. doi: 10.1016/j.jep.2023.117302. Epub 2023 Oct 18.
5
Essential oil composition and larvicidal activity of Saussurea lappa roots against the mosquito Aedes albopictus (Diptera: Culicidae).沙菀根挥发油成分及其对致倦库蚊幼虫的生物活性
Parasitol Res. 2012 Jun;110(6):2125-30. doi: 10.1007/s00436-011-2738-0. Epub 2011 Dec 14.
6
and as Therapeutic Agents against a Diabetic Rat Model-Approaches to Investigate Pharmacophore Modeling of Human IkB Kinase and Molecular Interaction with Dehydrocostus Lactone of .以及作为针对糖尿病大鼠模型的治疗剂——研究人IkB激酶药效团模型及与脱氢木香内酯分子相互作用的方法。
Metabolites. 2023 Jun 19;13(6):764. doi: 10.3390/metabo13060764.
7
Metabolomic insights into the therapeutic mechanisms of costus (Saussurea costus (Falc.) Lipsch.) root extract in propylthiouracil-induced hypothyroidism rat model.基于代谢组学对木香(木香(Falc.)Lipsch.)根提取物在丙硫氧嘧啶诱导的甲状腺功能减退大鼠模型中的治疗机制的见解。
J Ethnopharmacol. 2024 Apr 24;324:117784. doi: 10.1016/j.jep.2024.117784. Epub 2024 Jan 20.
8
Chemical characterization and the intrusion through elicitation and mediated hairy root transformation in C.B. Clarke.化学表征以及通过诱导和介导的发根转化在C.B.克拉克中的侵入。
Physiol Mol Biol Plants. 2023 Jan;29(1):87-91. doi: 10.1007/s12298-022-01270-9. Epub 2022 Dec 23.
9
HPLC-PDA Method for Quantification of Bioactive Compounds in Crude Extract and Fractions of Falc. and Cytotoxicity Studies against Cancer Cells.HPLC-PDA 法测定粗提物及 Fractions 中生物活性化合物的含量,并对其进行抗癌细胞毒性研究。
Molecules. 2023 Jun 16;28(12):4815. doi: 10.3390/molecules28124815.
10
Antioxidant and Anti-Urolithiatic Activity of Aqueous and Ethanolic Extracts from (Falc) Lispich Using Scanning Electron Microscopy.使用扫描电子显微镜对镰叶鼠麴草水提取物和乙醇提取物的抗氧化及抗尿路结石活性研究
Life (Basel). 2022 Jul 11;12(7):1026. doi: 10.3390/life12071026.

引用本文的文献

1
Cardioprotective, anti-inflammatory, and antioxidative outcome of costus against bleomycin-induced cardiotoxicity in rat model.闭鞘姜对博来霉素诱导的大鼠心脏毒性的心脏保护、抗炎和抗氧化作用
J Genet Eng Biotechnol. 2025 Mar;23(1):100466. doi: 10.1016/j.jgeb.2025.100466. Epub 2025 Feb 21.
2
Current and potential future biological uses of (Falc.) Lipsch: A comprehensive review.(Falc.)Lipsch的当前及未来潜在生物学用途:全面综述
Heliyon. 2024 Sep 11;10(18):e37790. doi: 10.1016/j.heliyon.2024.e37790. eCollection 2024 Sep 30.
3
The Anti-urolithiatic effect of the roots of (falc) Lipsch agonist ethylene glycol and magnesium oxide induced urolithiasis in rats.(镰叶)利普什的根对乙二醇和氧化镁诱导的大鼠尿路结石的抗尿路结石作用。 不过你提供的原文似乎不太完整准确,“(falc) Lipsch”这里不太明确具体所指。
Saudi Pharm J. 2024 Mar;32(3):101967. doi: 10.1016/j.jsps.2024.101967. Epub 2024 Feb 2.
4
Inhibitory Activity of Extract against Bacteria, Candida, Herpes, and SARS-CoV-2.提取物对细菌、念珠菌、疱疹和新型冠状病毒2的抑制活性。
Plants (Basel). 2023 Jan 19;12(3):460. doi: 10.3390/plants12030460.
5
Phytochemical Discrimination, Biological Activity and Molecular Docking of Water-Soluble Inhibitors from Herb against Main Protease of SARS-CoV-2.植物化学成分鉴别、水溶性抑制剂抗 SARS-CoV-2 主蛋白酶的生物活性及分子对接研究。
Molecules. 2022 Aug 1;27(15):4908. doi: 10.3390/molecules27154908.
6
Tentatively Identified (UPLC/T-TOF-MS/MS) Compounds in the Extract of Roots Exhibit In Vivo Hepatoprotection via Modulation of HNF-1α, Sirtuin-1, C/ebpα, miRNA-34a and miRNA-223.(UPLC/T-TOF-MS/MS)鉴定的提取物中的化合物通过调节 HNF-1α、Sirtuin-1、C/ebpα、miRNA-34a 和 miRNA-223 发挥体内肝保护作用。
Molecules. 2022 Apr 28;27(9):2802. doi: 10.3390/molecules27092802.
7
Exploring the inhibitory potential of and phytoconstituents against the Spike glycoprotein receptor binding domain of SARS-CoV-2 Delta (B.1.617.2) variant and the main protease (M) as therapeutic candidates, using Molecular docking, DFT, and ADME/Tox studies.利用分子对接、密度泛函理论(DFT)和药物代谢动力学/毒理学(ADME/Tox)研究,探索[具体物质]植物成分对严重急性呼吸综合征冠状病毒2(SARS-CoV-2)Delta(B.1.617.2)变体的刺突糖蛋白受体结合结构域和主要蛋白酶(M)的抑制潜力,以作为治疗候选物。
J Mol Struct. 2022 Sep 5;1263:133032. doi: 10.1016/j.molstruc.2022.133032. Epub 2022 Apr 9.
8
Exploring the Antifungal Activity and Action of Root Extracts against and Non- Species.探索根提取物对[未提及具体菌种]和非[未提及具体菌种]的抗真菌活性及作用。
Antibiotics (Basel). 2022 Mar 1;11(3):327. doi: 10.3390/antibiotics11030327.
9
In-vitro propagation and phytochemical profiling of a highly medicinal and endemic plant species of the Himalayan region (Saussurea costus).体外繁殖和高山地区(藏红花)特有药用植物的植物化学特征分析。
Sci Rep. 2021 Dec 8;11(1):23575. doi: 10.1038/s41598-021-03032-1.
10
Exhibits Anti-Oncogenic Effect in Hepatocellular Carcinoma, HepG2 Cancer Cell Line by Bcl-2 Mediated Apoptotic Pathway and Mitochondrial Cytochrome C Release.它通过 Bcl-2 介导的凋亡途径和线粒体细胞色素 C 释放,在肝癌、HepG2 癌细胞系中表现出抗癌作用。
Curr Issues Mol Biol. 2021 Sep 8;43(2):1114-1132. doi: 10.3390/cimb43020079.

本文引用的文献

1
Saussurea costus: botanical, chemical and pharmacological review of an ayurvedic medicinal plant.木香:一种阿育吠陀药用植物的植物学、化学和药理学综述
J Ethnopharmacol. 2007 Apr 4;110(3):379-90. doi: 10.1016/j.jep.2006.12.033. Epub 2007 Jan 20.
2
Chemical composition and antimicrobial activity of the essential oil of Cryptomeria japonica.日本柳杉精油的化学成分及抗菌活性
Phytother Res. 2007 Mar;21(3):295-9. doi: 10.1002/ptr.1864.
3
Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway.木香烯内酯,一种来自木香的倍半萜内酯,可抑制血管内皮生长因子受体KDR/Flk-1信号通路。
Cancer Lett. 2002 Dec 10;187(1-2):129-33. doi: 10.1016/s0304-3835(02)00361-0.
4
Germacrenes from fresh costus roots.新鲜木香根中的吉马烯类化合物。
Phytochemistry. 2001 Oct;58(3):481-7. doi: 10.1016/s0031-9422(01)00291-6.
5
Inhibitory effects of Oriental herbal medicines on IL-8 induction in lipopolysaccharide-activated rat macrophages.
Planta Med. 1995 Feb;61(1):26-30. doi: 10.1055/s-2006-957992.
6
Allergic contact dermatitis to costus: removal of haptens with polymers.
Acta Derm Venereol. 1981;61(6):525-9.