Eamsobhana Praphathip
Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Hawaii J Med Public Health. 2013 Jun;72(6 Suppl 2):28-32.
Cerebral angiostrongyliasis due to Angiostrongylus cantonensis continues to affect human health and productivity in Thailand. The dietary habits of the populace have been an important contributing factor, particularly in the northeast of the country where the disease is endemic and the indigenous people enjoy a local undercooked snail dish called "koi-hoi". Hundreds of cases of disease continue to be reported annually. Because of the difficulty in obtaining a definitive diagnosis, immunological methods have played an important role in the confirmation of A. cantonensis infection. Although enzyme-linked immunosorbent assay (ELISA) and immunoblot are test formats that have been used over the past decade, modern molecular approaches, such as PCR-based diagnostic techniques, are being developed and assessed as additional tests for the diagnosis of cerebral angiostrongyliasis. This short review focuses on the history, incidence, and laboratory diagnosis of angiostrongyliasis in Thailand.
由广州管圆线虫引起的脑型管圆线虫病持续影响着泰国的人类健康和生产力。民众的饮食习惯一直是一个重要的促成因素，特别是在该国东北部，该病为地方病，当地居民喜爱一种名为“koi-hoi”的当地未煮熟蜗牛菜肴。每年仍有数百例病例被报告。由于难以获得确切诊断，免疫方法在广州管圆线虫感染的确诊中发挥了重要作用。尽管酶联免疫吸附测定（ELISA）和免疫印迹是过去十年中使用的检测形式，但基于PCR的诊断技术等现代分子方法正在被开发和评估，作为脑型管圆线虫病诊断的补充检测方法。这篇简短综述聚焦于泰国管圆线虫病的历史、发病率及实验室诊断。
