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越南甲型H1N1pdm09流感死亡患者的流行病学和临床特征

Epidemiological and clinical characteristics of patients who died from Influenza A(H1N1)pdm09 in Viet Nam.

作者信息

Tinh Phan Thanh, Lan Phan Trong, Mahomed Patel, Nguyen Tran Minh Nhu

机构信息

Viet Nam Field Epidemiology Training Programme.

出版信息

Western Pac Surveill Response J. 2012 Feb 14;3(1):6-11. doi: 10.5365/WPSAR.2011.2.3.003. Print 2012 Jan.

Abstract

We describe the epidemiological and clinical characteristics of patients who died from influenza A(H1N1)pdm09 in hospitals in Viet Nam between August 2009 and March 2010. Of 58 fatal cases, 32 (55%) were below 30 years of age and 14 (24%) were pregnant females. Forty-five (78%) patients had at least one underlying medical condition including chronic heart, kidney or lung diseases or pregnancy. Twelve (21%) cases sought medical attention on the day of symptom onset. Only 13 (36%) of 36 cases for whom treatment data were available had been given antiviral drugs within the recommended two days of symptom onset. The clinical and epidemiologic characteristics of the patients who died from influenza A(H1N1)pdm09 are similar to those reported from other countries. To improve preparedness and response to future pandemics, Viet Nam needs to strengthen the surveillance of influenza; increase laboratory capacity to test for influenza viruses; and develop strategies for promoting the timely attendance of at-risk individuals at health facilities and the early administration of antiviral drugs, particularly for persons with underlying medical conditions and pregnant females.

摘要

我们描述了2009年8月至2010年3月期间在越南医院死于甲型H1N1流感大流行病毒(A(H1N1)pdm09)患者的流行病学和临床特征。在58例死亡病例中,32例(55%)年龄在30岁以下,14例(24%)为孕妇。45例(78%)患者至少有一种基础疾病,包括慢性心脏病、肾病或肺病或妊娠。12例(21%)病例在症状出现当天就医。在有治疗数据的36例病例中,只有13例(36%)在症状出现后的推荐两天内接受了抗病毒药物治疗。死于甲型H1N1流感大流行病毒(A(H1N1)pdm09)患者的临床和流行病学特征与其他国家报告的特征相似。为提高对未来大流行的防范和应对能力,越南需要加强流感监测;提高检测流感病毒的实验室能力;制定策略,促进高危个体及时前往医疗机构就诊,并尽早使用抗病毒药物,特别是对于有基础疾病的人和孕妇。

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