癫痫患者苯妥英中毒所致的不自主运动。
Involuntary movements caused by phenytoin intoxication in epileptic patients.
作者信息
Ahmad S, Laidlaw J, Houghton G W, Richens A
出版信息
J Neurol Neurosurg Psychiatry. 1975 Mar;38(3):225-31. doi: 10.1136/jnnp.38.3.225.
Abstract
The case histories of four patients who developed choreoathetoid movements during intoxication with phenytoin are presented. Drug intoxication was confirmed in each case by measuring the serum phenytoin concentration. Drug interactions were, in part, responsible for the occurrence of intoxication in three of them. Phenytoin intoxication is not always easy to recognize, particularly when nystagmus is minimal or absent, as in these four patients. The estimation of the serum phenytoin concentration is invaluable in this situation.
摘要
本文介绍了4例在苯妥英中毒期间出现舞蹈手足徐动症的患者的病例史。通过测量血清苯妥英浓度，在每例中均证实了药物中毒。药物相互作用在其中3例中毒的发生中起到了一定作用。苯妥英中毒并不总是容易识别，尤其是当眼球震颤轻微或不存在时，就像这4例患者一样。在这种情况下，血清苯妥英浓度的测定非常重要。
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