巴西南部一家新生儿重症监护病房的医院感染情况。
Nosocomial infections in a neonatal intensive care unit in South Brazil.
作者信息
Dal-Bó Karla, Silva Rosemeri Maurici da, Sakae Thiago Mamôru
出版信息
Rev Bras Ter Intensiva. 2012 Dec;24(4):381-5. doi: 10.1590/s0103-507x2012000400015.
Abstract
OBJECTIVE
The aim of this study was to describe the incidence and epidemiology of nosocomial infection in newborns who were admitted to a neonatal intensive care unit in a hospital in south Santa Catarina, Brazil.
METHODS
A prospective cohort study was conducted for 1 year among 239 neonates who remained as in-patients 48 hours after admission. The criteria that were used to diagnose infection were in accordance with the Centers for Disease Control and Prevention and the National Health Surveillance Agency.
RESULTS
The incidence of nosocomial infection was 45.8%. The primary reasons for admission were primary bloodstream infection (80.7%) and pneumonia (6.7%). Coagulase-negative Staphylococcus was the most commonly identified agent in the blood cultures and in the hospital unit. Prematurity was the most prevalent reason for admission. The general mortality rate was 12.1%, and mortality from nosocomial infection was 33.8%.
CONCLUSIONS
The incidence of nosocomial infection in the hospital unit was higher than rates that have been reported in other national studies. The major types of nosocomial infection were primary bloodstream infection and pneumonia.
摘要
目的
本研究旨在描述巴西圣卡塔琳娜州南部一家医院新生儿重症监护病房收治的新生儿医院感染的发生率及流行病学特征。
方法
对239名入院48小时后仍住院的新生儿进行了为期1年的前瞻性队列研究。诊断感染的标准符合疾病控制与预防中心及国家卫生监督局的标准。
结果
医院感染发生率为45.8%。入院的主要原因是原发性血流感染（80.7%）和肺炎（6.7%）。凝固酶阴性葡萄球菌是血培养及医院病房中最常鉴定出的病原体。早产是入院最常见的原因。总死亡率为12.1%，医院感染死亡率为33.8%。
结论
该医院病房的医院感染发生率高于其他国内研究报告的发生率。医院感染的主要类型是原发性血流感染和肺炎。
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