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细菌生物膜在器械相关感染中的作用。

The role of bacterial biofilms in device-associated infection.

机构信息

Sydney, Australia; and Dallas, Texas From the From the Surgical Infection Research Group, Macquarie University; and the Department of Plastic Surgery, University of Texas Southwestern Medical Center.

出版信息

Plast Reconstr Surg. 2013 Nov;132(5):1319-1328. doi: 10.1097/PRS.0b013e3182a3c105.

DOI:10.1097/PRS.0b013e3182a3c105
PMID:23924649
Abstract

There is increasing evidence that bacterial biofilm is responsible for the failure of medical devices, leading to device-associated infection. As plastic surgeons, we are among the leading users of prostheses in surgery, and it is important that we are kept informed of this growing problem. This article summarizes the pathogenesis of device-associated infection, outlines the evidence for such infection in a number of medical devices, and outlines operative strategies aimed at reducing the risk of bacterial contamination at the time of device deployment. It also outlines strategies under investigation to combat the development of device-associated infection.

摘要

越来越多的证据表明,细菌生物膜是导致医疗器械故障并引发器械相关感染的罪魁祸首。作为整形医生,我们是手术中使用假体的主要人群之一,因此了解这个日益严重的问题非常重要。本文总结了器械相关感染的发病机制,概述了几种医疗器械感染的证据,并概述了旨在降低器械部署时细菌污染风险的手术策略。本文还概述了正在研究的对抗器械相关感染发展的策略。

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The role of bacterial biofilms in device-associated infection.细菌生物膜在器械相关感染中的作用。
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