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耐甲氧西林金黄色葡萄球菌ST239谱系变种菌株BMB9393的全基因组序列，该菌株具有积累ica非依赖性生物膜的卓越能力。

Complete Genome Sequence of a Variant of the Methicillin-Resistant Staphylococcus aureus ST239 Lineage, Strain BMB9393, Displaying Superior Ability To Accumulate ica-Independent Biofilm.

作者信息

Costa Maiana Oliveira Cerqueira, Beltrame Cristiana Ossaille, Ferreira Fabienne Antunes, Botelho Ana Maria Nunes, Lima Nicholas Costa Barroso, Souza Rangel Celso, de Almeida Luiz Gonzaga Paula, Vasconcelos Ana Tereza Ribeiro, Nicolás Marisa Fabiana, Figueiredo Agnes Marie Sá

机构信息

Laboratório Nacional de Computação Científica, Laboratório de Bioinformática, Petrópolis, Rio de Janeiro, Brazil.

出版信息

Genome Announc. 2013 Aug 8;1(4):e00576-13. doi: 10.1128/genomeA.00576-13.

DOI:10.1128/genomeA.00576-13
PMID:23929475
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3738891/
Abstract

Biofilm is considered an important virulence factor in nosocomial infections. Herein, we report the complete genome sequence of a variant of methicillin-resistant Staphylococcus aureus, strain BMB9393, which is highly disseminated in Brazil. This strain belongs to the lineage ST239 and displays increased ability to accumulate ica-independent biofilm and to invade human epithelial cells.

摘要

生物膜被认为是医院感染中的一个重要毒力因子。在此，我们报告一株耐甲氧西林金黄色葡萄球菌变异株BMB9393的完整基因组序列，该菌株在巴西广泛传播。此菌株属于ST239谱系，具有增强的积累ica非依赖性生物膜以及侵袭人上皮细胞的能力。

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