免疫抑制剂雷帕霉素的产生菌雷帕霉素链霉菌菌株NRRL 5491的基因组序列草图
Draft Genome Sequence of Streptomyces rapamycinicus Strain NRRL 5491, the Producer of the Immunosuppressant Rapamycin.
作者信息
Baranasic Damir, Gacesa Ranko, Starcevic Antonio, Zucko Jurica, Blazic Marko, Horvat Marinka, Gjuracic Kresimir, Fujs Stefan, Hranueli Daslav, Kosec Gregor, Cullum John, Petkovic Hrvoje
机构信息
Acies Bio d.o.o., Ljubljana, Slovenia.
出版信息
Genome Announc. 2013 Aug 8;1(4):e00581-13. doi: 10.1128/genomeA.00581-13.
Abstract
Streptomyces rapamycinicus strain NRRL 5491 produces the important drug rapamycin. It has a large genome of 12.7 Mb, of which over 3 Mb consists of 48 secondary metabolite biosynthesis clusters.
摘要
雷帕霉素链霉菌菌株NRRL 5491可产生重要药物雷帕霉素。它拥有一个1270万个碱基对的大基因组，其中超过300万个碱基对由48个次生代谢物生物合成簇组成。
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