Finnish Food Safety Authority Evira, Helsinki, Finland.
Epidemiol Infect. 2010 Nov;138(11):1581-5. doi: 10.1017/S0950268810000373. Epub 2010 Mar 3.
In Finland, rabies in bats was suspected for the first time in 1985 when a bat researcher, who had multiple bat bites, died in Helsinki. The virus isolated from the researcher proved to be antigenically related to rabies viruses previously detected in German bats. Later, the virus was typed as EBLV-2b. Despite an epidemiological study in bats 1986 and subsequent rabies surveillance, rabies in bats was not detected in Finland until the first case in a Daubenton's bat (Myotis daubentonii) was confirmed in August 2009. The bat was paralysed, occasionally crying, and biting when approached; it subsequently tested positive for rabies. The virus was genetically typed as EBLV-2. This is the northernmost case of bat rabies ever detected in Europe. Phylogenetic analyses showed that the EBLV-2b isolate from the human case in 1985 and the isolate from the bat in 2009 were genetically closely related, demonstrating that EBLV-2 may have been circulating in Finland for many years.
1985 年，一名曾被多次蝙蝠咬伤的蝙蝠研究人员在赫尔辛基死亡，芬兰首次怀疑蝙蝠携带狂犬病。从该研究人员身上分离出的病毒被证明与先前在德国蝙蝠身上检测到的狂犬病病毒在抗原上具有相关性。随后，该病毒被鉴定为 EBLV-2b。尽管 1986 年对蝙蝠进行了流行病学研究，并随后进行了狂犬病监测，但直到 2009 年 8 月首次在一只达氏蝙蝠（Myotis daubentonii）身上确诊狂犬病病例，芬兰才发现蝙蝠携带狂犬病。这只蝙蝠出现瘫痪、偶尔尖叫和咬人等症状，随后狂犬病检测呈阳性。该病毒被基因鉴定为 EBLV-2。这是欧洲有记录以来最北的蝙蝠狂犬病病例。系统进化分析显示，1985 年人类病例中的 EBLV-2b 分离株和 2009 年蝙蝠分离株在基因上密切相关，表明 EBLV-2 可能在芬兰流行了多年。
