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社区获得性耐喹诺酮大肠杆菌肾盂肾炎合并多发性肾脓肿:一例报告

Community acquired quinolone-resistant Escherichia coli pyelonephritis complicated with multiple renal abscesses: a case report.

作者信息

Katsiari M, Nikolaou C, Roussou Z, Triantopoulou C, Apessou D, Platsouka Ed, Maguina A

机构信息

Intensive Care Unit, Konstantopouleio General Hospital, Athens, Greece.

出版信息

Hippokratia. 2012 Oct;16(4):381-3.

PMID:23935324
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3738619/
Abstract

Acute pyelonephritis is a potentially organ-damaging and life-threatening infection. A 37-year old woman was admitted to Intensive Care Unit in septic shock and multi-organ failure due to acute pyelonephritis with systemic bacterial dissemination caused by a quinolone-resistant Escherichia coli. The patient, a previously healthy woman, reported recurrent episodes of urinary tract infection in the previous 3 years, which were treated with quinolones. Treatment course with broad-spectrum antimicrobial agents reversed her septic shock and multi-organ failure. However, pyelonephritis progressed to intrarenal and perirenal abscesses formation. The patient fully recovered after surgical removal of the infected kidney.

摘要

急性肾盂肾炎是一种可能损害器官并危及生命的感染。一名37岁女性因耐喹诺酮的大肠杆菌引起的急性肾盂肾炎伴全身细菌播散,以感染性休克和多器官衰竭被收入重症监护病房。该患者此前身体健康,报告在过去3年中有复发性尿路感染,曾用喹诺酮类药物治疗。使用广谱抗菌药物的治疗过程逆转了她的感染性休克和多器官衰竭。然而,肾盂肾炎进展为肾内和肾周脓肿形成。患者在手术切除感染的肾脏后完全康复。

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本文引用的文献

1
Risk factors for fluoroquinolone-resistant Escherichia coli in adults with community-onset febrile urinary tract infection.成人社区获得性发热性尿路感染中氟喹诺酮耐药大肠埃希菌的危险因素。
J Antimicrob Chemother. 2011 Mar;66(3):650-6. doi: 10.1093/jac/dkq465. Epub 2010 Dec 1.
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Renal abscesses measuring 5 cm or less: outcome of medical treatment without therapeutic drainage.直径 5 厘米或以下的肾脓肿:无需治疗性引流的药物治疗结果。
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Renal and perirenal abscesses in patients with otherwise anatomically normal urinary tracts.尿路解剖结构正常的患者发生肾脓肿和肾周脓肿。
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Risk factors for community-acquired ciprofloxacin-resistant Escherichia coli urinary tract infection.社区获得性耐环丙沙星大肠杆菌尿路感染的危险因素。
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Quinolone resistance among Escherichia coli strains from community-acquired urinary tract infections in Greece.希腊社区获得性尿路感染大肠杆菌菌株中的喹诺酮耐药性。
Clin Microbiol Infect. 2004 Jan;10(1):75-8. doi: 10.1111/j.1469-0691.2004.00807.x.
7
Medical treatment of renal and perirenal abscesses: CT evaluation.肾及肾周脓肿的药物治疗:CT评估
Clin Radiol. 1999 Dec;54(12):792-7. doi: 10.1016/s0009-9260(99)90680-3.
8
Perinephric and intrarenal abscesses.
Urology. 1985 Dec;26(6):529-36. doi: 10.1016/0090-4295(85)90353-x.