Department of Dermatology, Venereology and Allergology, University Clinic of Essen, Germany.
J Dtsch Dermatol Ges. 2013 Nov;11(11):1057-63. doi: 10.1111/ddg.12170. Epub 2013 Aug 15.
In almost every chronic wound different bacteria species can be detected.
Retrospective, multicenter evaluation of bacterial swab results from 2010 and 2011 in patients with chronic leg ulcer treated in 10 dermatologic wound care centers from 5 regions in Germany.
Data of 970 patients were analyzed. Staphylococcus aureus was detected in 47.6 % of the patients, 8.6% of these were methicillin-resistant (MRSA). Pseudomonas aeruginosa was found in 31.1 %, enterobacteria in 28.6 % and Proteus mirabilis in 13.7 % of the patients. The regional comparison showed a significant south-north gradient for S. aureus, P. aeruginosa, and enterobacteria. Moreover, a highly significant west-east gradient for MRSA was found with detection rates of 13.5 % in the west to 4.0 % in the east. Furthermore, nationally there was a significant negative correlation between S. aureus and P. aeruginosa or P. mirabilis, respectively, as well as a positive correlation of P. aeruginosa with respect to wound size and duration. In addition to climatic and therapeutic conditions, different regional health care structures are discussed as potentially relevant reasons for these significantly different regional detection rates.
Our data show the regional variability of the spectrum of currently detected bacteria in patients with chronic leg ulcers in Germany.
在几乎每一种慢性创伤中都可以检测到不同的细菌种类。
回顾性、多中心评估了 2010 年至 2011 年德国 5 个地区的 10 个皮肤科伤口护理中心治疗的慢性腿部溃疡患者的细菌拭子结果。
分析了 970 名患者的数据。金黄色葡萄球菌在 47.6%的患者中被检测到，其中 8.6%为耐甲氧西林金黄色葡萄球菌（MRSA）。绿脓假单胞菌在 31.1%的患者中被发现，肠杆菌在 28.6%的患者中被发现，奇异变形杆菌在 13.7%的患者中被发现。区域比较显示，金黄色葡萄球菌、绿脓假单胞菌和肠杆菌存在显著的南北梯度。此外，还发现了 MRSA 的高度显著的东西梯度，西部的检出率为 13.5%，东部为 4.0%。此外，全国范围内，金黄色葡萄球菌与绿脓假单胞菌或奇异变形杆菌之间存在显著的负相关，绿脓假单胞菌与伤口大小和持续时间之间存在显著的正相关。除了气候和治疗条件外，不同的区域医疗保健结构也被认为是这些明显不同的区域检测率的潜在相关原因。
我们的数据显示了德国慢性腿部溃疡患者中当前检测到的细菌谱的区域性差异。
