Reproductive health and midwifery department, Tarbiat Modares University, Tehran, Iran.
Health Qual Life Outcomes. 2013 Aug 16;11:141. doi: 10.1186/1477-7525-11-141.
The aim of the present study was to estimate the prevalence of mood disorders and examine a range of predictors for psychological well-being among Iranian women with polycystic ovary syndrome (PCOS).
A cross-sectional study was undertaken to ascertain the factors related to psychological distress in PCOS patients in Kashan, Iran. Psychological distress was measured using the Hospital Anxiety and Depression Scale (HADS). In addition we assessed quality of life using the Short Form Health Survey (SF-36). Socio-demographic details and clinical information of PCOS including obesity (body mass index), excessive body hair (hirsutism score), acne, menstrual cycle disturbances, infertility and endocrine profile also were recorded for each patient.
In all 300 women with PCOS were entered into the study. Of these 32% (n =96) showed elevated HADS anxiety while depression was high in 5% (n =15). Quality of life was significantly impaired in women with anxiety (P <0.05), and depression (P <0.001) and in particular, in women with coexistence anxiety and depression (P <0.001) compared with unaffected participants. Compared with the non-depressed PCOS patients, the depressed women had significantly higher menstrual irregularities (P = 0.008). Moreover, we found significant difference in FAI level between the depressed and non depressed (p = 0.05), the anxious and non anxious patients (p < 0.001) compare to non affected PCOS women.
The high prevalence of depression and anxiety in this population suggests that initial evaluation of all women with PCOS should also include assessment of mental health disorders. The clinician should further pay attention to background of their patients especially in view of the factors influencing psychological well-being.
本研究旨在估计伊朗多囊卵巢综合征（PCOS）女性中情绪障碍的患病率，并探讨一系列与心理健康相关的预测因素。
采用横断面研究，确定伊朗卡尚 PCOS 患者心理困扰的相关因素。使用医院焦虑抑郁量表（HADS）评估心理困扰。此外，我们还使用简明健康调查问卷（SF-36）评估生活质量。记录每位患者的社会人口统计学资料和 PCOS 的临床信息，包括肥胖（体重指数）、多毛症（多毛症评分）、痤疮、月经周期紊乱、不孕和内分泌谱。
共有 300 名 PCOS 女性进入研究。其中 32%（n=96）出现 HADS 焦虑升高，5%（n=15）出现抑郁。焦虑（P<0.05）和抑郁（P<0.001）的女性生活质量明显受损，尤其是焦虑和抑郁并存的女性（P<0.001）与未受影响的参与者相比。与非抑郁 PCOS 患者相比，抑郁患者的月经不规则（P=0.008）明显更高。此外，我们发现抑郁组和非抑郁组（p=0.05）、焦虑组和非焦虑组（p<0.001）的 FAI 水平有显著差异，与未受影响的 PCOS 女性相比。
该人群中抑郁和焦虑的高患病率表明，对所有 PCOS 女性的初始评估还应包括心理健康障碍的评估。临床医生应进一步关注患者的背景，特别是在影响心理健康的因素方面。
