Asundep Ntui N, Jolly Pauline E, Carson April, Turpin Cornelius A, Zhang Kui, Tameru Berhanu
Department of Epidemiology, School of Public Health, University of Alabama at Birmingham (UAB), 1665 University Boulevard, RPHB 217, Birmingham, AL, 35294, USA,
Matern Child Health J. 2014 Jul;18(5):1085-94. doi: 10.1007/s10995-013-1338-2.
Antenatal care (ANC) has been shown to influence infant and maternal outcomes. WHO recommends 4 ANC visits for uncomplicated pregnancies. However, pregnant women in Ghana are required to attend 8-13 antenatal visits. We investigated the association of ANC attendance with adverse pregnancy outcomes (defined as low infant birth weight, stillbirth, preterm delivery or small for gestational age). A quantitative cross-sectional study was conducted on 629 women, age 19-48 years who presented for delivery at two selected public hospitals and 16 traditional birth attendants from July to November 2011. Socio-demographic and antenatal information were collected using a structured questionnaire. ANC attendance, medical and obstetric/gynecological history were abstracted from maternal antenatal records. Data were analyzed using Chi square and logistic regression. Twenty-two percent of the women experienced an adverse outcome. Eleven percent of the women attended <4 ANC visits. In an unadjusted model, these women had an increased likelihood of experiencing an adverse outcome (OR 2.27; 95% CI 1.30-3.94; p = 0.0038). High parity (>5 children) was also associated with adverse birth outcomes. Women screened for syphilis or use of insecticide-treated bed nets had a 40 and 36% (p = 0.0447 and p = 0.0293) reduced likelihood of experiencing an adverse pregnancy outcome respectively. After adjusting for confounders, attending <4 antenatal visits was associated with adverse pregnancy outcome compared with ≥4 ANC visits (Adjusted OR 2.55; 95% CI 1.16-5.63; p = 0.0202). Attending <4 antenatal visits and high parity were associated with adverse pregnancy outcomes for uncomplicated pregnancies.
产前保健(ANC)已被证明会影响母婴结局。世界卫生组织建议无并发症的孕妇进行4次产前检查。然而,加纳的孕妇需要进行8至13次产前检查。我们调查了产前检查次数与不良妊娠结局(定义为低出生体重儿、死产、早产或小于胎龄儿)之间的关联。2011年7月至11月,对在两家选定公立医院分娩的629名年龄在19至48岁的妇女以及16名传统助产士进行了一项定量横断面研究。使用结构化问卷收集社会人口学和产前信息。从产妇产前记录中提取产前检查次数、医疗和妇产科病史。使用卡方检验和逻辑回归分析数据。22%的妇女经历了不良结局。11%的妇女产前检查次数少于4次。在未调整的模型中,这些妇女经历不良结局的可能性增加(比值比2.27;95%置信区间1.30 - 3.94;p = 0.0038)。高胎次(>5个孩子)也与不良分娩结局相关。接受梅毒筛查或使用经杀虫剂处理的蚊帐的妇女经历不良妊娠结局的可能性分别降低了40%和36%(p = 0.0447和p = 0.0293)。在对混杂因素进行调整后,如果将产前检查次数≥4次作为参照,那么产前检查次数少于4次与不良妊娠结局相关(调整后比值比2.55;95%置信区间1.16 - 5.63;p = 0.0202)。对于无并发症的妊娠,产前检查次数少于4次和高胎次与不良妊娠结局相关。