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2004-2011 年芬兰基于人群的注册研究:会阴切开术和肛门括约肌损伤风险分层关联的变化。

Changing associations of episiotomy and anal sphincter injury across risk strata: results of a population-based register study in Finland 2004-2011.

机构信息

Department of Obstetrics and Gynaecology, Kuopio University Hospital, Kuopio, Finland.

出版信息

BMJ Open. 2013 Aug 17;3(8):e003216. doi: 10.1136/bmjopen-2013-003216.

Abstract

OBJECTIVES

To evaluate the changing association between lateral episiotomy and obstetric anal sphincter injury (OASIS) for women with low and high baseline risk of OASIS.

DESIGN

A population-based register study.

SETTING

Data gathered from the Finnish Medical Birth Register for the years 2004-2011.

PARTICIPANTS

All women with spontaneous vaginal or vacuum-assisted singleton births in Finland (n=384 638).

MAIN OUTCOME MEASURE

OASIS incidence.

RESULTS

During the study period, the incidence of OASIS increased from 1.3% to 1.7% in women with first vaginal births, including women admitted for first vaginal birth after a prior caesarean section and from 0.1% to 0.3% in women with at least one prior birth, whereas episiotomy rates declined from 56.7% to 45.5% and 10.1- 5.3%, respectively. At the study onset, when episiotomy was used more widely, it was negatively associated with OASIS in women with first vaginal births, but as episiotomy use declined it became positively associated with OASIS. Women with episiotomy were complicated by OASIS with clearly higher risk scores than women without episiotomy suggesting that episiotomy was clearly protective against OASIS. OASIS occurred with lower mean risk scores among women with and without episiotomy over time. However, OASIS incidences increased only among women with episiotomy, whereas it decreased or remained among women without episiotomy.

CONCLUSIONS

The cross-over effect between episiotomy and OASIS could be explained by increasing disparity in baseline OASIS risk between treated and untreated women, since episiotomy use declined most in women at low OASIS risk. Episiotomy rate can be safely reduced in low-risk women but interestingly along with the policy change the practice to cut the episiotomy became less protective among high-risk women.

摘要

目的

评估低位和高位产科肛门括约肌损伤(OASIS)基线风险的女性中,会阴侧切术与 OASIS 之间关联的变化。

设计

基于人群的注册研究。

设置

数据来自芬兰医疗出生登记处 2004 年至 2011 年的数据。

参与者

芬兰所有自发性阴道或真空辅助单胎分娩的女性(n=384638)。

主要观察指标

OASIS 发生率。

结果

在研究期间,首次阴道分娩的女性 OASIS 发生率从 1.3%增加到 1.7%,包括经剖宫产转为首次阴道分娩的女性,且至少有一次分娩史的女性 OASIS 发生率从 0.1%增加到 0.3%,而会阴切开术率从 56.7%下降到 45.5%和 10.1%至 5.3%。在研究开始时,当会阴切开术应用更广泛时,它与首次阴道分娩的女性 OASIS 呈负相关,但随着会阴切开术使用率的下降,它与 OASIS 呈正相关。行会阴切开术的女性 OASIS 风险评分明显高于未行会阴切开术的女性,这表明会阴切开术明显能预防 OASIS。随着时间的推移,行或未行会阴切开术的女性的 OASIS 平均风险评分均降低。然而,仅在行会阴切开术的女性中 OASIS 发生率增加,而未行会阴切开术的女性中 OASIS 发生率降低或保持不变。

结论

会阴切开术与 OASIS 之间的交叉效应可以通过治疗和未治疗女性之间 OASIS 基线风险差异的增大来解释,因为会阴切开术的使用率在低 OASIS 风险女性中下降最多。在低危女性中,可以安全地降低会阴切开术的使用率,但有趣的是,随着政策的变化,会阴切开术的实施对高危女性的保护作用降低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6efa/3752051/012d527b2eee/bmjopen2013003216f01.jpg

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