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环境表观遗传学及其对男性生育力的影响。

Environmental epigenetics and effects on male fertility.

机构信息

Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA, 99164-4236, USA.

出版信息

Adv Exp Med Biol. 2014;791:67-81. doi: 10.1007/978-1-4614-7783-9_5.

Abstract

Environmental exposures to factors such as toxicants or nutrition can have impacts on testis biology and male fertility. The ability of these factors to influence epigenetic mechanisms in early life exposures or from ancestral exposures will be reviewed. A growing number of examples suggest environmental epigenetics will be a critical factor to consider in male reproduction.

摘要

环境暴露于毒物或营养等因素会对睾丸生物学和男性生育能力产生影响。本文将回顾这些因素在早期生活暴露或祖先暴露中影响表观遗传机制的能力。越来越多的例子表明,环境表观遗传学将是男性生殖中需要考虑的一个关键因素。

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