Department of Pharmaceutical Sciences, Faculty of Pharmacy, Federal University of Juiz de Fora, São Pedro, Juiz de Fora, Minas Gerais 36036-330, Brazil.
Molecules. 2013 Aug 16;18(8):9785-96. doi: 10.3390/molecules18089785.
The chemical composition of the essential oils obtained by hydrodistillation of different parts of Eremanthus erythropappus, including leaves, branches and inflorescences, was investigated by Gas Chromatography and Gas Chromatography/Mass Spectrometry. The antimicrobial activity of the oils was assessed by the disc diffusion and microdilution methods, while the antioxidant activity was evaluated by DPPH and reducing power tests. The main compounds found in the essential oils derived from the inflorescences and leaves were β-caryophyllene, germacrene-D, α-copaene and β-pinene. α-Bisabolol was the major component in the branches. The oils were active against Staphylococcus aureus, Streptococcus pyogenes and fungi, but not Escherichia coli and Pseudomonas aeruginosa. The MIC values ranged from 0.01 to 0.50 mg/mL. Using the DPPH test, the IC50 values ranged from 38.77 ± 0.76 to 102.24 ± 1.96 μg/mL, while the reducing power test produced IC50 values between 109.85 ± 1.68 and 169.53 ± 0.64 μg/mL. The results revealed that the E. erythropappus oils are new promising potential sources of antimicrobial and antioxidant compounds with good future practical applications for human health.
通过水蒸气蒸馏法从伊兰香不同部位（包括叶、枝和花序）中提取精油，并采用气相色谱和气相色谱/质谱联用技术对其化学成分进行了研究。采用圆盘扩散法和微量稀释法评估了精油的抗菌活性，采用 DPPH 和还原力试验评估了抗氧化活性。从花序和叶中提取的精油的主要成分是 β-石竹烯、大根香叶烯 D、α-古巴烯和β-蒎烯。α-红没药醇是枝条中的主要成分。这些油对金黄色葡萄球菌、化脓性链球菌和真菌具有活性，但对大肠杆菌和铜绿假单胞菌没有活性。MIC 值范围为 0.01 至 0.50mg/mL。使用 DPPH 试验，IC50 值范围为 38.77±0.76 至 102.24±1.96μg/mL，而还原力试验产生的 IC50 值范围为 109.85±1.68 至 169.53±0.64μg/mL。结果表明，伊兰香精油是具有抗菌和抗氧化活性的新的有前途的化合物来源，对人类健康具有良好的实际应用前景。
