Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Jamia Hamdard (Hamdard University), New Delhi 110 062, India.
Saudi Pharm J. 2013 Jan;21(1):1-12. doi: 10.1016/j.jsps.2012.03.002. Epub 2012 Mar 29.
Quinoline or 1-aza-naphthalene is a weak tertiary base. Quinoline ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. Quinoline not only has a wide range of biological and pharmacological activities but there are several established protocols for the synthesis of this ring. The article aims at highlighting these very diversities of the ring.
喹啉或 1-氮萘是一种弱的叔胺。已发现喹啉环具有抗疟、抗菌、抗真菌、驱虫、强心、抗惊厥、抗炎和镇痛活性。喹啉不仅具有广泛的生物和药理活性,而且有几种已建立的合成该环的方法。本文旨在强调该环的这些多样性。