Lee Myoung-Heon, Jeoung Hye-Young, Lim Ji-Ae, Song Jae-Young, Song Dae-Sub, An Dong-Jun
Animal, Plant and Fisheries Quarantine and Inspection Agency, Anyang, Gyeonggi-do 430-824, Republic of Korea.
Virus Genes. 2012 Aug;45(1):186-9. doi: 10.1007/s11262-012-0745-6. Epub 2012 Apr 12.
Kobuviruses have been detected in humans and several animal species, including cattle, swine, sheep, canines, mice, and probably bats. While investigating the possibility of Kobuviruses infecting additional animal host species, we detected kobuvirus in three fecal samples from domestic Korean black goats. In a maximum parsimony tree and a Bayesian tree, the 08KG680 strain fell within the bovine kobuvirus lineage, but the 09KG172 and 10KG056 strains did not fall within any of the known animal kobuvirus lineages. Comparative analysis of the partial nucleotide sequences of the RNA-dependent RNA polymerase (RdRp) gene of the 08KG680 strain also revealed high amino acid sequence identity and a close genetic relationship with bovine kobuvirus, but the amino acid sequences of the other two strains had low similarity to those of known kobuvirus isolates from any animal species. The similarity of the sequence of the 08KG680 strains with the bovine kobuvirus indicate that the infectious may have originated from cattle, but the possible source for remaining strains could not be classified.
人们已在人类和几种动物物种中检测到杯状病毒,包括牛、猪、羊、犬、小鼠,可能还有蝙蝠。在调查杯状病毒感染其他动物宿主物种的可能性时,我们从韩国本土黑山羊的三份粪便样本中检测到了杯状病毒。在最大简约树和贝叶斯树中,08KG680毒株属于牛杯状病毒谱系,但09KG172和10KG056毒株不属于任何已知的动物杯状病毒谱系。对08KG680毒株的RNA依赖性RNA聚合酶(RdRp)基因部分核苷酸序列的比较分析还显示,其与牛杯状病毒具有高度的氨基酸序列同一性和密切的遗传关系,但其他两个毒株的氨基酸序列与来自任何动物物种的已知杯状病毒分离株的氨基酸序列相似性较低。08KG680毒株序列与牛杯状病毒的相似性表明,这种感染可能源自牛,但其余毒株的可能来源无法归类。