Farahmand Farahmand, Choobi Anzali Babak, Heshmat Ramin, Ghafouri Hamed-Basir, Hamedanchi Sepehr
Department of Emergency, Imam-Khomeini Hospital, Keshavarz Boulevard, 1419733141 Tehran, Iran.
Malays J Med Sci. 2013 May;20(3):39-43.
We aim to assess serum sodium and potassium levels in patients with different types of cerebro-vascular accidents (CVA) in comparison to control group.
A comparative cross-sectional study conducted on patients admitted to the emergency department from January to August 2012. Control group consisted of patients admitted to emergency department due to common cold, urinary tract infection, low back pain, cluster, and tension headache or migraine. Serum sodium and potassium levels were measured via standard laboratory methods.
There were 77 patients in control group and 78 in CVA group. Forty nine patients from the CVA group had ischemic CVA, 11 had hemorrhagic CVA and 18 suffered a transient ischemic attack (TIA). Serum sodium level in control group was significantly lower than in patients with TIA, ischemic CVA, and hemorrhagic CVA (P < 0.001). Serum potassium level in control group was higher than patients with TIA, ischemic CVA, and hemorrhagic CVA (P < 0.001). Patients with hemorrhagic CVA showed significantly lower serum potassium level than patients with TIA and ischemic CVA (P < 0.001). Correspondingly, it was observed that serum sodium to potassium ratio was higher in patients with TIA, ischemic CVA, and hemorrhagic CVA (P < 0.001). In patients with hemorrhagic CVA serum sodium to potassium ratio was higher when compared to patients with TIA and ischemic CVA (P < 0.001).
This study shows that higher serum sodium and lower serum potassium level may be associated with higher incidence of CVA. Further studies are paramount to elucidate the role of serum electrolyte levels in vascular events.
我们旨在评估不同类型脑血管意外(CVA)患者的血清钠和钾水平,并与对照组进行比较。
对2012年1月至8月入住急诊科的患者进行了一项比较性横断面研究。对照组由因普通感冒、尿路感染、腰痛、丛集性头痛、紧张性头痛或偏头痛而入住急诊科的患者组成。通过标准实验室方法测量血清钠和钾水平。
对照组有77例患者,CVA组有78例患者。CVA组中49例为缺血性CVA,11例为出血性CVA,18例为短暂性脑缺血发作(TIA)。对照组的血清钠水平显著低于TIA、缺血性CVA和出血性CVA患者(P < 0.001)。对照组的血清钾水平高于TIA、缺血性CVA和出血性CVA患者(P < 0.001)。出血性CVA患者的血清钾水平显著低于TIA和缺血性CVA患者(P < 0.001)。相应地,观察到TIA、缺血性CVA和出血性CVA患者的血清钠钾比更高(P < 0.001)。与TIA和缺血性CVA患者相比,出血性CVA患者的血清钠钾比更高(P < 0.001)。
本研究表明,较高的血清钠水平和较低的血清钾水平可能与CVA的较高发病率相关。进一步的研究对于阐明血清电解质水平在血管事件中的作用至关重要。