Fu Tsung-Hao, McElroy William T, Shamszad Mariam, Heidebrecht Richard W, Gulledge Brian, Martin Stephen F
Department of Chemistry and Biochemistry, The University of Texas at Austin, 1 University Station A5300, Austin, TX 78712-0165, USA.
Tetrahedron. 2013 Jul 8;69(27-28):5588-5603. doi: 10.1016/j.tet.2013.03.010.
The formal syntheses of -methylwelwitindolinone C isothiocyanate () and several other welwitindolinones - were achieved by the independent synthesis of . The synthesis featured a Lewis acid-mediated coupling between a heteroaryl carbinol and bis-TMS enol ether, an intramolecular enolate arylation, and an unprecedented intramolecular allylic alkylation of a γ-acyloxyenone.
通过独立合成实现了-甲基维特吲哚啉酮C异硫氰酸酯（）和其他几种维特吲哚啉酮的形式合成。该合成的特点是杂芳基甲醇与双三甲基硅基烯醇醚之间的路易斯酸介导偶联、分子内烯醇盐芳基化以及前所未有的γ-酰氧基烯酮分子内烯丙基烷基化。
