水杨酸基聚（酸酐 - 酯）的优化合成
Optimized Synthesis of Salicylate-based Poly(anhydride-esters).
作者信息
Schmeltzer Robert C, Anastasiou Theodore J, Uhrich Kathryn E
机构信息
Department of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ 08854-8087.
出版信息
Polym Bull (Berl). 2013 Mar 1;49(6):441-448. doi: 10.1007/s00289-003-0123-6.
Abstract
The synthesis of a salicylate-based poly(anhydride-ester) was optimized to improve the overall efficiency and quality of the polymer. First, a new approach for the preparation of the polymer precursor minimizes the overall number of synthetic steps and increases the overall yield. Second, the melt-polymerization apparatus was modified to include dynamic mixing, which yields polymer with increased molecular weights on both the milligram and gram scale.
摘要
基于水杨酸酯的聚（酸酐-酯）的合成工艺得到了优化，以提高聚合物的整体效率和质量。首先，一种制备聚合物前体的新方法减少了合成步骤的总数并提高了总产率。其次，对熔融聚合设备进行了改进，使其具备动态混合功能，从而能够在毫克和克规模上制备出分子量更高的聚合物。
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