Philip Ajay, Thomas Regi, Job Anand, Sundaresan V Rajan, Anandan Shalini, Albert Rita Ruby
Department of ENT Unit-1, Christian Medical College, Indian Subcontinent, Vellore 632004, India.
ISRN Otolaryngol. 2013 Jul 25;2013:239730. doi: 10.1155/2013/239730. eCollection 2013.
Objectives. Otomycosis is a common ENT disease frequenting the tropics. Its recurrent nature poses a great challenge to the treating physician. In spite of a number of antifungals in the market, the frequent nature of this disease warrants repeated use of these drugs, contributing to drug resistance and financial burden on the rural population. Our primary aims were to evaluate the effectiveness of povidone iodine in the treatment of otomycosis and to identify the most common fungal isolate in our population. Study Design and Setting. A single blinded prospective longitudinal study was done over a period of 12 months in a tertiary referral center. 34 patients in the age group 15-70 years clinically diagnosed with otomycosis were included in this study. These individuals were divided into two groups selected randomly. One arm received 7.5% povidone iodine otic drops and the other 1% Clotrimazole and lignocaine drops. Evaluation was based on resolution of symptoms and signs after treatment. Result. Both arms showed improvements which were comparable thus suggesting the role of povidone iodine in the management of otomycosis. Conclusion. Povidone iodine is an effective antifungal in the treatment of otomycosis.
目的。耳真菌病是一种常见于热带地区的耳鼻喉科疾病。其复发性给治疗医生带来了巨大挑战。尽管市场上有多种抗真菌药物，但这种疾病的频发特性使得这些药物需要反复使用，这导致了耐药性以及给农村人口带来经济负担。我们的主要目的是评估聚维酮碘治疗耳真菌病的有效性，并确定我们研究人群中最常见的真菌分离株。研究设计与背景。在一家三级转诊中心进行了一项为期12个月的单盲前瞻性纵向研究。本研究纳入了34名年龄在15至70岁之间临床诊断为耳真菌病的患者。这些个体被随机分为两组。一组接受7.5%聚维酮碘耳滴剂，另一组接受1%克霉唑和利多卡因滴剂。评估基于治疗后症状和体征的缓解情况。结果。两组均有改善，且具有可比性，这表明聚维酮碘在耳真菌病治疗中的作用。结论。聚维酮碘是治疗耳真菌病的一种有效抗真菌药物。
