Department of Naturopathy, Blankenstein Hospital, Ruhr-Universität Bochum , Hattingen , Germany .
Gynecol Endocrinol. 2013 Dec;29(12):1022-5. doi: 10.3109/09513590.2013.831836. Epub 2013 Sep 2.
Menopausal symptoms management with high-quality plant extracts from Actaea (Cimicifuga. racemosa rootstock is well-established. Efficacy and safety are supported by research and clinical trials since several decades and backed up by official monographs. However, the recent published Cochrane review on black cohosh neglects major evidence for beneficial effects. The authors' negative conclusions are questionable and call for reply and clarification. Our careful reconsideration of all appropriate placebo-controlled clinical studies reveals a standardized mean difference of 0.385 in favor of black cohosh (p < 0.0001).
使用高质量的植物提取物（如升麻属植物）来管理更年期症状已得到广泛认可。几十年来，多项研究和临床试验都证实了其疗效和安全性，并得到了官方专论的支持。然而，最近发表的 Cochrane 评论忽视了黑升麻有益效果的主要证据。作者的负面结论值得商榷，需要回应和澄清。我们仔细重新审议了所有适当的安慰剂对照临床试验，结果显示黑升麻组的标准化均数差值为 0.385（p<0.0001），有利于黑升麻。
