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儿童阻塞性睡眠呼吸暂停综合征。

Obstructive sleep apnea syndrome in childhood.

机构信息

School of Medicine, University of Insubria, Varese, Italy.

出版信息

Early Hum Dev. 2013 Oct;89 Suppl 3:S33-7. doi: 10.1016/j.earlhumdev.2013.07.020. Epub 2013 Aug 27.

Abstract

Obstructive sleep apnea syndrome (OSAS) was first reported in 1976 by Guilleminault. This condition has been defined as a disorder of breathing during sleep characterized by prolonged partial/complete upper airway obstruction that disrupts normal ventilation and normal sleep patterns. The prevalence of this condition varies among the different populations but it is between 1 and 2% in preschool children when adenoid and tonsils volume has a major peak. Loud snoring is very common in these children but not always present. The diagnosis may be suggested by the facial appearance and by personal history but it must be confirmed by a polysomnography recording. OSAS has many associated morbidities which involve the cardiovascular system, the neurocognitive performance, the growth and the metabolic homeostasis. Obesity is a common associated condition and it impairs the therapeutic success. It should be considered when planning the treatment program: it should be stressed the obesity epidemic has already reached the European countries and it is now contributing to the "adult type" of OSAS which was quite rare in childhood until few years ago. The adenotonsillectomy is the most common therapeutic intervention but it is curative only in 2/3 of patients. Orthodontic approaches, associated with orofacial muscle reinforcing physiotherapy are helpful in most of these patients. To conclude we must stress that this condition is quite common and should be promptly diagnosed to prevent the multisystem morbidities; a multidisciplinary approach should be always offered to the parents of these children.

摘要

阻塞性睡眠呼吸暂停综合征(OSAS)于 1976 年由 Guilleminault 首次报道。这种情况被定义为一种睡眠期间的呼吸障碍,其特征是上气道长时间部分/完全阻塞,扰乱正常通气和正常睡眠模式。这种情况的患病率在不同人群中有所不同,但在腺样体和扁桃体体积达到高峰的学龄前儿童中为 1%至 2%。这些儿童中经常出现响亮的鼾声,但并非总是存在。通过面部特征和个人病史可以提示诊断,但必须通过多导睡眠图记录来确认。OSAS 有许多相关的并发症,涉及心血管系统、神经认知表现、生长和代谢稳态。肥胖是一种常见的相关疾病,会影响治疗效果。在制定治疗计划时应考虑到这一点:肥胖症已经在欧洲国家流行,现在它导致了“成人型”OSAS,这种情况在几年前还很少见。腺样体扁桃体切除术是最常见的治疗干预措施,但仅对 2/3 的患者有效。正畸方法,结合口面肌肉强化物理疗法,对大多数患者都有帮助。最后我们必须强调,这种情况很常见,应及时诊断以预防多系统并发症;应始终为这些儿童的家长提供多学科方法。

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