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经皮侧方经椎间孔入路治疗成人退变性脊柱侧凸是否可行?

Is the lateral transpsoas approach feasible for the treatment of adult degenerative scoliosis?

机构信息

Department of Minimally Invasive Spine Surgery, Instituto de Patologia da Coluna, Rua Vergueiro 1421, Sala 305, Torre Sul, 04101-000, São Paulo, SP, Brazil.

出版信息

Clin Orthop Relat Res. 2014 Jun;472(6):1776-83. doi: 10.1007/s11999-013-3263-5.

Abstract

BACKGROUND

Lumbar degenerative scoliosis is a common condition in the elderly. Open traditional surgical approaches are associated with high-morbidity complication rates. Less invasive options may carry fewer risks in this patient population. A minimally disruptive lateral transpsoas retroperitoneal technique to accomplish interbody fusion was developed to avoid the morbidity of traditional open surgery, but this approach as an anterior stand-alone construction has not been reported yet for the treatment of adult degenerative scoliosis.

QUESTIONS/PURPOSES: We determined (1) the clinical outcomes (VAS scores for back and leg, Oswestry Disability Index), (2) the radiographic outcomes (Cobb angle, lumbar lordosis, sacral slope, high-grade subsidence, osseous fusion), and (3) the reoperation and complication rates in an older population undergoing this surgical approach.

METHODS

Between 2004 and 2008, 62 patients were treated surgically for adult degenerative scoliosis, of whom 46 (74%) were treated with stand-alone lateral lumbar interbody fusion; 11 of these (24%) were lost to followup before 24 months, leaving the records of 35 patients (nine men, 26 women; mean ± SD age, 68 ± 10 years) available for this retrospective review. General indications for this approach included neurogenic claudication and radicular symptoms with history of chronic low-back pain. A total of 107 levels were treated (mean, three; range, one to seven). Clinical and radiographic outcomes were assessed at a followup of 24 months.

RESULTS

Mean VAS back pain scores improved from 85 mm preoperatively to 27 mm at latest followup (p < 0.001). VAS leg pain scores improved from 91 mm to 24 mm (p < 0.001). Oswestry Disability Index scores improved from 51 to 29 (p < 0.001). Coronal alignment improved from Cobb angles of 21° to 12° (p < 0.001). Lumbar lordosis improved from 33° to 41° (p < 0.001). Sacral slope was enhanced from 28° to 35° (p < 0.001). Fusion rate was 84% at final evaluation. High-grade subsidence was seen in 10 patients (29%). Three patients (9%) needed further surgical intervention.

CONCLUSIONS

Use of the lateral approach achieved reasonable coronal and sagittal correction, as well as improvements in pain and function, in mild scoliotic deformities; however, subsidence was a concern, occurring in 29% of patients. Questions still remain regarding the need for additional supplementation or the use of wider cages to prevent subsidence.

LEVEL OF EVIDENCE

Level IV, therapeutic study. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

腰椎退行性脊柱侧凸是老年人的常见病症。传统的开放式手术方法与高发病率的并发症发生率相关。对于这类患者人群,微创选择可能风险更小。为了避免传统开放式手术的发病率,我们开发了一种微创经侧方经椎间孔腹膜后技术来实现椎体间融合,但这种方法作为一种独立的前路手术方法,尚未有报道用于治疗成人退行性脊柱侧凸。

问题/目的:我们确定了(1)临床结果(背部和腿部的视觉模拟评分、Oswestry 残疾指数),(2)影像学结果(Cobb 角、腰椎前凸、骶骨倾斜、高级沉降、骨融合),以及(3)在老年人群中进行这种手术方法的再次手术和并发症发生率。

方法

在 2004 年至 2008 年间,有 62 名患者接受了成人退行性脊柱侧凸的手术治疗,其中 46 名(74%)接受了独立的侧路腰椎椎间融合术治疗;11 名(24%)在 24 个月前失访,因此,35 名患者(9 名男性,26 名女性;平均年龄 ± 标准差,68 ± 10 岁)的记录可供回顾性分析。该方法的一般适应证包括神经源性跛行和根性症状,伴有慢性下腰痛病史。共治疗了 107 个节段(平均 3 个,范围 1 至 7 个)。在 24 个月的随访时评估临床和影像学结果。

结果

平均 VAS 背部疼痛评分从术前的 85 毫米改善至末次随访时的 27 毫米(p < 0.001)。VAS 腿部疼痛评分从 91 毫米改善至 24 毫米(p < 0.001)。Oswestry 残疾指数评分从 51 改善至 29(p < 0.001)。冠状面矫正从 Cobb 角 21°改善至 12°(p < 0.001)。腰椎前凸从 33°改善至 41°(p < 0.001)。骶骨倾斜从 28°改善至 35°(p < 0.001)。最终评估时融合率为 84%。10 名患者(29%)出现高级沉降。3 名患者(9%)需要进一步手术干预。

结论

在轻度脊柱侧凸畸形中,使用侧方入路可获得合理的冠状面和矢状面矫正,以及疼痛和功能的改善,但沉降是一个问题,29%的患者出现沉降。关于是否需要额外的补充或使用更宽的椎间融合器来预防沉降,仍存在疑问。

证据水平

IV 级,治疗性研究。请参阅作者说明,以获取完整的证据水平描述。

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