用于纳米医学应用的无孔二氧化硅纳米颗粒。
Nonporous Silica Nanoparticles for Nanomedicine Application.
作者信息
Tang Li, Cheng Jianjun
机构信息
Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, 61801, USA.
出版信息
Nano Today. 2013 Jun;8(3):290-312. doi: 10.1016/j.nantod.2013.04.007.
Abstract
Nanomedicine, the use of nanotechnology for biomedical applications, has potential to change the landscape of the diagnosis and therapy of many diseases. In the past several decades, the advancement in nanotechnology and material science has resulted in a large number of organic and inorganic nanomedicine platforms. Silica nanoparticles (NPs), which exhibit many unique properties, offer a promising drug delivery platform to realize the potential of nanomedicine. Mesoporous silica NPs have been extensively reviewed previously. Here we review the current state of the development and application of nonporous silica NPs for drug delivery and molecular imaging.
摘要
纳米医学，即将纳米技术应用于生物医学领域，有潜力改变许多疾病的诊断和治疗格局。在过去几十年里，纳米技术和材料科学的进步催生了大量有机和无机纳米医学平台。具有许多独特性质的二氧化硅纳米颗粒（NPs）为实现纳米医学的潜力提供了一个有前景的药物递送平台。介孔二氧化硅纳米颗粒此前已得到广泛综述。在此，我们综述无孔二氧化硅纳米颗粒在药物递送和分子成像方面的发展现状及应用。
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