Lamminen A E, Tanttu J I, Sepponen R E, Pihko H, Korhola O A
Department of Radiology, University Central Hospital, Helsinki, Finland.
Br J Radiol. 1993 Sep;66(789):783-7. doi: 10.1259/0007-1285-66-789-783.
T1 rho dispersion, or the frequency dependence of T1 relaxation in the rotating frame, was used for in vivo muscle tissue characterization in 13 patients with primary skeletal muscle disease and in eight normal subjects for comparison. T1 rho dispersion measurements represent a new approach to magnetic resonance tissue characterization, possibly reflecting the macromolecular constituents of tissue. A definite, statistically significant, difference was found between the relative T1 rho dispersion values of normal and diseased muscle tissue. T1 rho dispersion measurements and images may increase the accuracy of identification of diseased muscles. Early identification of affected muscles is important for accurate diagnosis by muscle biopsy.
T1ρ弥散，即旋转坐标系中T1弛豫的频率依赖性，被用于对13例原发性骨骼肌疾病患者的体内肌肉组织进行特征分析，并与8名正常受试者进行比较。T1ρ弥散测量代表了一种磁共振组织特征分析的新方法，可能反映了组织的大分子成分。在正常和患病肌肉组织的相对T1ρ弥散值之间发现了明确的、具有统计学意义的差异。T1ρ弥散测量和图像可能会提高患病肌肉识别的准确性。早期识别受影响的肌肉对于通过肌肉活检进行准确诊断很重要。
